ThYme: Thioester-active Enzymes

Families - ACS

Acyl-CoA synthases form thioester bonds, mainly between acyl chains and coenzyme A (CoA), but also among other substrates.

Family Names of enzymes and genes present
ACS1

AMP-binding protein
Long-chain-fatty-acid-CoA ligase
FadD
4-chlorobenzoate-CoA ligase
Acetyl-CoA synthetase
acsA
Benzoate-CoA ligase
Short-chain-fatty-acid-CoA ligase
fadK
Long-chain-fatty-acid-ACP ligase
mbtM
4-hydroxybenzoyl-CoA synthetase
2-succinylbenzoate-CoA ligase
3-hydroxybenzoyl-CoA ligase
Medium-chain fatty acid-CoA ligase
4-coumarate-CoA ligase
4CLL1, 4CLL2, 4CLL5, 4CLL6, 4CLL7, 4CLL8, 4CLL9, 4CL1, 4CL2, 4CL3, 4CL4
Acetoacyl-CoA synthetase
Long-chain-acyl-CoA synthetase
LACS1, LACS2, LACS3, LASC4, LACS5, LACS6, LACS7, LACS8, LACS9,
Acyl-CoA synthetase mitochondrial
ACSM1, ACSM2, ACSM3, ACSM4, ACSM5
Fatty acyl-CoA synthetase A, fcsA
Acetyl-CoA synthetase, ACSS1, ACSS2
Acyl-CoA synthase family member, ACSF2, ACSF3

ACS2

BioW
6-carboxyhexanoate-CoA ligase
Pimeloyl-CoA synthase

ACS3

Citrate lyase ligase
citC
[Citrate (pro-3S)-lyase]-ligase

ACS4

Phenylacetate-CoA ligase
paaK
 

ACS5

Succinyl-CoA synthetase alpha chain (sucD)
Succinyl-CoA ligase subunit beta (sucC)