ThYme: Thioester-active Enzymes

Family BCCP1

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Names of enzymes and/or genes present

Biotin carboxyl carrier protein

EC numbers
Catalytic residues
Notes
Numbers [P] (Evidence at Protein Level) = 43
[T] (Evidence at Transcript Level) = 115
PDBs = 38
Archaea
Sequence EC Number Organism GenBank ID RefSeq UniProt PDB
149aa long hypothetical methylmalonyl-CoA decarboxylase gamma chain {ECO:0000313|EMBL:BAA30387.1} Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3). BAA30387.1
NP_143172.1
WP_010885371.1
O57883 [P]
O59021 [P]
2D5D
2EJF
2EJG
2EVB
Bacteria
Sequence EC Number Organism GenBank ID RefSeq UniProt PDB
Biotin/lipoyl attachment protein {ECO:0000313|EMBL:CEI57017.1} 6.4.1.2 {ECO:0000313|EMBL:KDE23583.1}
Bacillus subtilis. AAF08803.1
ADM37926.1
AFQ57759.1
AGG61199.1
AHA77864.1
AIC40248.1
AIC44480.1
AIY93134.1
AIY97442.1
AJD36490.1
AJE94514.1
AJW87263.1
BAM52478.1
BAM58054.1
CAX52627.1
CEI57017.1
EFG93067.1
EME07347.1
EXF53321.1
KDE23583.1
KFC32508.1
KFH29725.1
KFH36147.1
KFK79827.1
KIX83090.1
WP_003220179.1
WP_003245519.1
YP_003097733.1
A0A063XAC4
C0H419 [P]
C0H419.1
E0TWI0
L8AIM8
1Z6H
1Z7T
2B8F
2B8G
Acetyl-CoA carboxylase, biotin carboxyl carrier protein {ECO:0000313|EMBL:EGK17974.1} 6.4.1.2 {ECO:0000313|EMBL:KGY80455.1}
Escherichia coli 908658. AAA23408.1
AAA23744.1
AAA23745.1
AAA58058.1
AAB24892.1
AAC76287.1
AAG58383.1
AAN82451.1
BAB37550.1
BAE77296.1
CAA32933.1
CCK48564.1
CDK47092.1
CDK83712.1
CDL06249.1
CDL26214.1
CDL42603.1
CDN83992.1
EDU92228.1
EFI86873.1
EFJ74146.1
EFJ87149.1
EFJ98644.1
EFK01255.1
EFK21083.1
EFK26792.1
EFK43602.1
EFK50850.1
EFK68164.1
EFK74731.1
EFK89608.1
EFO60053.1
EFU37149.1
EFX19384.1
EFZ59115.1
EGB61867.1
EGB65600.1
EGB89987.1
EGE63037.1
EGI09649.1
EGI20311.1
EGI44716.1
EGI49716.1
EGP23514.1
EGW87830.1
EGW92878.1
EHP65862.1
EHU05866.1
EHU06551.1
EHU19644.1
EHU22814.1
EHU36557.1
EHU39264.1
EHU41514.1
EHU51686.1
EHV53741.1
EHX23604.1
EHX27567.1
EHX28592.1
EID68047.1
EIG81215.1
EIG93730.1
EIH14192.1
EIH24621.1
EII12692.1
EII25121.1
EII37017.1
EII44283.1
EII57440.1
EIL57205.1
EKJ83634.1
ELC14565.1
ELC36596.1
ELC57211.1
ELD96220.1
ELE53211.1
ELE57874.1
ELF06788.1
ELI22174.1
ELI35922.1
ELJ68265.1
ELW30669.1
EMU58880.1
EMV53180.1
EMV54074.1
EMX18981.1
EMX29819.1
EMX37039.1
EMX47201.1
EMX83570.1
ENA04988.1
ENA29073.1
ENA38180.1
ENB09568.1
ENB37522.1
ENC30449.1
ENC38164.1
ENC89711.1
END50640.1
END89093.1
ENG95164.1
ENH07163.1
EOU56732.1
EOU88319.1
EOU88538.1
EOV02698.1
EOV09748.1
EOV16069.1
EOV54705.1
EOV62276.1
EOV70514.1
EOV72476.1
EOV75466.1
EOW00943.1
EOW02630.1
EOW03516.1
EOW11071.1
EOW19151.1
EOW29939.1
EOW42304.1
EOW94294.1
EQN24360.1
EQN90973.1
EQP46016.1
EQQ02208.1
EQR35947.1
EQW89619.1
EQX49374.1
EQX67251.1
EQX85561.1
EQY57152.1
EQY81136.1
EQZ33325.1
EQZ98322.1
ERB02251.1
ERB25230.1
ESA31565.1
ESA65391.1
ESA65809.1
ESA66046.1
ESA75024.1
ESA93176.1
ESA97540.1
ESC93360.1
ESC99510.1
ESD11679.1
ESD19933.1
ESD37073.1
ESD38147.1
ESD63896.1
ESD67273.1
ESD72527.1
ESD84462.1
ESE11082.1
ESK15734.1
ESK33626.1
ESP07592.1
ETE26343.1
ETJ21752.1
ETS25627.1
ETY42104.1
EYE21084.1
EYV14835.1
EZA36044.1
EZB62546.1
EZD89177.1
EZD93954.1
EZJ36425.1
EZJ49224.1
EZJ70315.1
EZJ81491.1
EZJ83118.1
EZK20271.1
KDG92875.1
KDU20222.1
KDU27111.1
KDU32769.1
KDU54138.1
KDU63626.1
KDV36873.1
KDV41115.1
KDV63380.1
KDW29514.1
KDW73203.1
KDW84576.1
KDX21885.1
KDX88368.1
KDY23906.1
KDY52279.1
KDY59413.1
KDY60062.1
KDY87560.1
KDY94447.1
KDZ16338.1
KDZ39138.1
KDZ61510.1
KEJ44569.1
KEJ48407.1
KEJ58298.1
KEJ66511.1
KEJ73007.1
KEL28247.1
KEL69389.1
KEM51485.1
KEN46389.1
KEN65020.1
KEN87736.1
KEN95370.1
KEN97637.1
KEO07545.1
KEO22260.1
KEO29292.1
KGM62043.1
NP_289823.1
NP_312154.1
NP_417721.1
NP_755877.1
YP_491437.1
A0A017LD38
A0A025CMH8
A0A026V1X4
A0A027F8L8
A0A027YSG1
A0A027Z5M8
A0A029HJK1
A0A029IKU7
A0A029KB88
A0A029L941
A0A029LCB1
A0A029PD24
A0A064TF62
A0A069XDE9
A0A069XSH3
A0A069Z3G8
A0A070D6X9
A0A070DKV4
A0A070FBX9
A0A070KCM6
A0A070P7G3
A0A070PU13
A0A070SWQ1
A0A070YMZ8
A0A071AL49
A0A071BYL3
A0A071CP19
A0A071DDK3
A0A071ET27
A0A073FRW0
A0A073GJW6
A0A073GNL6
A0A073HHW9
A0A073TH29
A0A073V560
A0A074HM46
A0A074HT71
A0A074IFJ8
A0A079A5Y0
A0A079B590
A0A079DP40
A0A079F6A1
A0A079FLF6
A0A079GTW2
A0A079XUN1
A0A080BUJ4
A0A080EEF1
A0A080FTC3
A0A080GJU9
A0A080I2Y2
A0A080IKR4
A0A0A0FI80
B3BEM8
D7X6G5
D7XNB2
D7Y132
D7YN66
D7ZQP1
D8A710
D8C2K4
D8EE61
D8EN24
E1HR50
E1HYW1
E1ILL0
E1J7I6
E6BFV9
E7I8L0
E8HZN6
E9T9V4
E9YIX9
E9YV04
F1ZN26
F4SNY3
F4TK21
F4VJQ2
F4W0D9
F7N1N5
G2ALD0
G2B004
H1BXB1
H3KTQ6
H4I1S3
H4IXR9
H4JCW1
H4JST1
H4KMM4
H4L396
H4LHU9
H4UPW6
H5IPP8
H5J7A5
H5JP02
I0VV81
I2RG30
I2S0G4
I2SV00
I2W209
I2WKE3
I2X1Z2
I2X5L3
I2XTH8
I4T3B4
J7RXF4
K5BVR4
L2VJD8
L2X9V4
L2YZ28
L3KB49
L3PYJ7
L3QDI7
L3UEC5
L4V355
L4W7F5
L5H1B6
L9HY05
M8JWK2
M8T965
M8TJS9
M9G861
M9GB48
M9GWX9
M9IIS4
M9K9S0
N2H6T6
N2J5M1
N2JL44
N2QCS0
N2STV7
N3A6W9
N3AVE7
N3FDS4
N3JVT0
N3NAE4
N4NEM6
N4NZN3
P0ABD8 [P]
P0ABD9
P0ABE0
P24182 [P]
S0V5L5
S0X854
S0XR60
S0YW65
S0ZFZ3
S0ZGK1
S1D753
S1D880
S1DW71
S1E2D7
S1EAW8
S1GHK2
S1GQ32
S1H7W1
S1HUJ1
S1IH78
S1JD19
S1KDA7
S1PMB0
T5P3R4
T5UK01
T6H7L0
T6LHZ1
T6XUJ0
T8T2W5
T8Y1L7
T8YPP1
T9A6Q6
T9G024
T9IRE8
T9N0J4
T9S4F4
U0AY17
U0DRI6
U9VG39
U9XUS2
U9XVJ9
U9XXD3
U9YKM0
V0A613
V0AUI9
V0REZ2
V0RXD3
V0SYL2
V0U8F4
V0UYC8
V0VM86
V0X5L2
V0XR59
V0Y453
V0YQB3
V1AZK9
V2T068
V2T7I8
V4BNX6
V6E6E0
V6FKA7
V8KND4
W1BUM5
W1DDN5
W1EVN3
W1G9H3
W1WU67
W3UQ03
W8ZXN0
X7P388
1A6X
1BDO
2BDO
3BDO
4HR7
pyruvate carboxylase Listeria monocytogenes AAT03866.1
AFH79651.1
AGR05622.1
AGR11378.1
AGR15468.1
AGR16742.1
AGR20700.1
AGR22634.1
AGR26073.1
AHJ35146.1
AHN32329.1
AHY98718.1
AIZ38367.1
AJA82782.1
AJT44849.1
CAS04854.1
CBY03636.1
CBY48662.1
CBY67147.1
CBY69989.1
CBY72853.1
CBY75709.1
CCO63675.1
EEW19000.1
EFF96769.1
EFK40455.1
EGF37956.2
EGF46091.1
ERH80062.1
ERH80245.1
ERH82521.1
ERH85927.1
ERH86881.1
EXL17174.1
EXL25489.1
KES33330.1
KES33918.1
KES42481.1
KES43616.1
KES46801.1
KES47164.1
KES51544.1
KES56313.1
KES59676.1
KES61012.1
KES67640.1
KES68315.1
KES68760.1
KES74707.1
KES77177.1
KES78146.1
KES80761.1
KES83439.1
KES90206.1
KES93453.1
KES95793.1
KET02855.1
KET03956.1
KET05516.1
KET10441.1
KET13802.1
KET14240.1
KET18370.1
KET20724.1
KET34205.1
KET35895.1
KET40374.1
KET42516.1
KET45475.1
KET49545.1
KET51702.1
KET54301.1
KET59503.1
KET61893.1
KET65706.1
KET72062.1
KET76190.1
KET78900.1
KET80173.1
KET84650.1
KET87679.1
KET89813.1
KET94005.1
KET95505.1
KET99264.1
KEU05668.1
KEU07386.1
KEU10341.1
KEU15613.1
KEU17388.1
KEU19409.1
KEU20141.1
KEU26294.1
KEU29778.1
KEU31159.1
KEU38260.1
KEU44374.1
KEU46859.1
KEU49701.1
KEU54426.1
KEU57705.1
KEU63327.1
KEU67452.1
KEU71510.1
KEU72544.1
KEU81558.1
KEU91647.1
KEU93036.1
KEU99232.1
KEV03036.1
KEV07411.1
KEV13102.1
KEV17817.1
KEV22350.1
KEV24041.1
KEV29864.1
KEV31142.1
KEV37497.1
KEV39425.1
KEV46099.1
KEV48147.1
KEV50315.1
KEV56261.1
KEV57053.1
KEV64289.1
KEV65145.1
KEV65939.1
KEV68608.1
KEV72666.1
KEV77594.1
KEV79638.1
KEV84037.1
KEV85083.1
KEV91869.1
KEV92945.1
KEV94546.1
KEV96567.1
KEW02822.1
KEW07465.1
KEW08991.1
KEW10745.1
KEW16575.1
KEW23173.1
KEW24560.1
KEW27261.1
KEW29331.1
KEW34177.1
KEW36496.1
KEW39971.1
KEW46112.1
KEW48919.1
KEW57124.1
KEW62387.1
KEW66509.1
KEW67559.1
KEW73239.1
KEW75008.1
KEW75621.1
KEW80924.1
KEW82614.1
KEW87524.1
KEW90387.1
KEW94667.1
KEW97714.1
KEX00849.1
KEX09157.1
KEX12651.1
KEX18012.1
KEX21523.1
KEX24930.1
KEX27542.1
KEX31919.1
KEX32811.1
KEX36231.1
KEX42347.1
KEX45643.1
KEX52412.1
KEX62666.1
KEX65487.1
KEX67771.1
KEX71834.1
KEX77439.1
KEX78932.1
KEX79578.1
KEX84061.1
KFZ70555.1
KGJ78050.1
KGJ83460.1
KGR19476.1
KHK10038.1
KHK25325.1
KHK39854.1
WP_003731550.1
YP_006681520.1
YP_013689.1
C1L1Y9
F3RJ30
Q720Z8
4QSL
Putative methylmalonyl-CoA carboxyltransferase {ECO:0000313|EMBL:CAD59402.1} 2.1.3.1
2.1.3.1 {ECO:0000313|EMBL:CAD59402.1}
2.1.3.1 {ECO:0000313|EMBL:CEI24550.1}
Propionibacterium freudenreichii subsp. shermanii. AAA25674.1
AJQ91496.1
CAD59402.1
CBL57376.1
CDP49157.1
CEG86413.1
CEG88429.1
CEG90361.1
CEG94092.1
CEG96045.1
CEH00733.1
CEH03685.1
CEH04708.1
CEH08811.1
CEH10692.1
CEP27759.1
WP_013161729.1
A0A068VTF8
A0A0A8S1A8
D7GFR5
P02904 [P]
P02904.1
Q546E3
1DCZ
1DD2
1O78
Acetyl-CoA carboxylase, biotin carboxylase subunit {ECO:0000313|EMBL:EMZ49240.1} Pseudomonas aeruginosa str. Stone 130. AAG05400.1
AGV58870.1
AGV65400.1
AGY67851.1
AGY70107.1
EHS37066.1
EJZ76725.1
EKA37671.1
EMZ49240.1
ERU52083.1
ERU58389.1
ERW92861.1
ERX02156.1
ERX20934.1
ERY03852.1
ERY99156.1
ERZ31213.1
ETV47786.1
EZN62098.1
EZO30703.1
KDR49164.1
KEA29244.1
NP_250702.1
WP_003113506.1
YP_008552235.1
YP_008557902.1
YP_008693875.1
YP_008706156.1
N2CED4
Q9I297
Q9I299
3U9S
3U9T
Pyruvate carboxylase {ECO:0000256|PIRNR:PIRNR001594} 6.4.1.1 {ECO:0000256|PIRNR:PIRNR001594}
Rhizobium etli. AAC44388.1
ABC92746.1
WP_011427190.1
Q2K340
Q59740
2QF7
3TW6
3TW7
propionyl-CoA carboxylase, alpha subunit Ruegeria pomeroyi DSS-3 AAV94401.1
WP_011046848.1
Q168G2
Q5LUF3
3N6R
D Chain D, Crystal Structure Of K442e Mutant Of S. Aureus Pyruvate Carboxylase Staphylococcus aureus ABQ48974.1
ABR52050.1
ACY10989.1
ADC37282.1
AHM68783.1
BAB42211.1
BAB57276.1
BAF77989.1
CBX34350.1
CDP39450.1
CDP43277.1
CDP46098.1
CDP59227.1
EEV27467.1
EEV65736.1
EEV66533.1
EEV75403.1
EEV79663.1
EEV85584.1
EFB94761.1
EFC03756.1
EFG45373.1
EFH36014.1
EFT86287.1
EGG61695.1
EGS93617.1
EHO97940.1
EHS10397.1
EHS13350.1
EHS30335.1
EHT19928.1
EHT20276.1
EHT39640.1
EHT40122.1
EHT50667.1
EHT55735.1
EHT81600.1
EHT90784.1
EID41027.1
EIK07107.1
EIK07536.1
EIK08738.1
EIK13506.1
EIK16049.1
EIK18418.1
EIK23776.1
EIK25281.1
EIK25371.1
EIK32184.1
EIK32738.1
EIK34663.1
EJU81495.1
ELS67367.1
EMY94534.1
EMY95420.1
EMY98286.1
EMZ00806.1
EMZ06166.1
EMZ07125.1
EMZ12860.1
ENI52202.1
ENI58261.1
ENI62072.1
ENI62577.1
ENI68844.1
ENI69656.1
ENI76097.1
ENI77419.1
ENI78593.1
ENI83141.1
ENI85734.1
ENI85781.1
ENI91503.1
ENI92432.1
ENI93714.1
ENI97908.1
ENJ03636.1
ENJ04189.1
ENJ07508.1
ENJ09138.1
ENJ12301.1
ENJ15518.1
ENJ16012.1
ENJ20339.1
ENJ26438.1
ENJ27404.1
ENJ32278.1
ENJ35601.1
ENJ41805.1
ENJ44000.1
ENJ44994.1
ENJ52878.1
ENJ54502.1
ENJ56229.1
ENJ62615.1
ENJ65000.1
ENJ66858.1
ENJ72845.1
ENJ73888.1
ENJ80269.1
ENJ81943.1
ENJ84264.1
ENJ88226.1
ENJ88731.1
ENJ94855.1
ENJ96339.1
ENJ97485.1
ENK03504.1
ENK10255.1
ENK12975.1
ENK18040.1
ENK21530.1
ENK22633.1
ENK27171.1
ENK28180.1
ENK33572.1
ENK35399.1
ENK42320.1
ENK43852.1
ENK50477.1
ENK58248.1
ENK58911.1
ENK61907.1
ENK66469.1
ENK68329.1
ENK76574.1
ENK77776.1
ENK78086.1
ENK83703.1
ENK84905.1
ENK89119.1
ENK94967.1
ENK98257.1
ENL01225.1
ENL02890.1
ENL09568.1
ENL15225.1
ENL16707.1
ENL18470.1
ENL21378.1
ENL25543.1
ENL27404.1
ENL31234.1
ENL31289.1
ENL37320.1
ENL48095.1
ENL51052.1
ENL56109.1
ENL57176.1
ENL60458.1
ENL61451.1
ENL64929.1
ENL70728.1
ENL71751.1
ENL74129.1
ENL76730.1
ENL84756.1
ENL85152.1
ENL86660.1
ENL92416.1
ENL95074.1
ENL99774.1
ENM00584.1
ENM01706.1
ENM06520.1
ENM07247.1
ENM18784.1
ENM19007.1
ENM21584.1
ENM25765.1
ENM26713.1
ENM29032.1
ENM34205.1
ENM35419.1
ENM36593.1
ENM41099.1
ENM41634.1
ENM46503.1
ENM53240.1
ENM54553.1
ENM59337.1
ENM59679.1
ENM69354.1
ENM69426.1
ENM75117.1
ENM82303.1
ENM85067.1
ENM86919.1
ENM89419.1
ENM90850.1
ENM94839.1
ENM95900.1
ENM96652.1
ENN05240.1
ENN05484.1
ENN06224.1
ENN13499.1
ENN14807.1
ENN20504.1
ENN24180.1
ENN28530.1
ENN30175.1
ENN31667.1
ENN35341.1
ENN35848.1
ENN38998.1
ENN42232.1
ENN46224.1
ENN48278.1
ENN53003.1
ENN55967.1
ENN60399.1
ENN62723.1
ENN66276.1
ENN68819.1
EOR33390.1
EOR90065.1
EPR25051.1
EPX92781.1
ETD14729.1
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KDA10229.1
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KIT84505.1
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KIX75969.1
WP_000809514.1
A5IS01
A6U0T2
A7X125
D0K429
D3EVK9
Q7A666
Q99UY8
3BG5
3HB9
3HBL
3HO8
4HNT
4HNU
4HNV
Eukaryota
Sequence EC Number Organism GenBank ID RefSeq UniProt PDB
Biotin carboxylase 6.3.4.14
6.4.1.2 {ECO:0000269|PubMed:16854592
ECO:0000269|PubMed:20952656}
Homo sapiens (Human). AAB58382.1
AAC50571.1
AAI72264.1
AAI72569.1
AAR37018.1
ABF48723.1
CAE01470.2
CAE01471.3
EAW97853.1

O00763 [P]
2DN8
2KCC
3TDC
Pyruvate carboxylase {ECO:0000256|PIRNR:PIRNR001594} 6.4.1.1
6.4.1.1 {ECO:0000256|PIRNR:PIRNR001594}
Homo sapiens (Human). AAA36423.1
AAA60033.1
AAA82937.1
AAA99537.1
AAB31500.1
AAH11617.1
AIC49340.1
BAG60062.1
BAI45576.1
EAW74568.1
EAW74569.1
EAW74570.1
EAW74571.1
EAW74572.1
NP_000911.2
NP_001035806.1
NP_071504.2
XP_005274088.1
XP_005274089.1
XP_006718640.1
XP_006718641.1
XP_011543387.1
XP_011543388.1
A0A024R5C5
P11498 [P]
P11498-1
P11498.2
3BG3
3BG9
3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha 6.4.1.4
Homo sapiens (Human). AAG50245.1
AAG53095.1
AAH04187.1
AAH04214.1
AAK67986.1
BAA99407.1
BAB14377.1
BAD92974.1
CAH18403.1
EAW78340.1
NP_001280202.1
NP_064551.3
Q68D27 [T]
Q96RQ3 [P]
Q96RQ3.3
2EJM
Biotin carboxylase 6.3.4.14
6.4.1.2 {ECO:0000269|PubMed:12663926
ECO:0000269|PubMed:15079078}
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). AAA20073.1
CAA96294.1
DAA10557.1
EIW08105.1
NP_014413.1
N1P4Q3
Q00955 [P]
Q00955.2
4WYO
4WZ8