ThYme: Thioester-active Enzymes

Family ER5

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Names of enzymes and/or genes present

Mitochondrial enoyl-ACP reductases (ETR1)

Enoyl-ACP reductases

Mitochondrial trans-2-enoyl-CoA reductases (MECRs)

Enoyl-CoA reductases
 

EC numbers

1.3.1.- (Unclassified reductases)

1.3.1.10 (enoyl-[acyl carrier protein] reductase)

1.3.1.38 (Trans-2-enoyl-CoA reductases)
 

Catalytic residues
Notes
Numbers [P] (Evidence at Protein Level) = 9
[T] (Evidence at Transcript Level) = 18
PDBs = 9
Eukaryota
Sequence EC Number Organism GenBank ID RefSeq UniProt PDB
Probable trans-2-enoyl-CoA reductase, mitochondrial 1.3.1.38
Arabidopsis thaliana (Mouse-ear cress). AAL32632.1
AAM47974.1
AAM64465.1
AEE78071.1
CAB75790.1
NP_566881.1
Q8LCU7 [T]
Q8LCU7-1
Q8LCU7.1

MECR protein {ECO:0000313|EMBL:AAI11153.1} Bos taurus (Bovine). AAI11153.1

Q2TA23 [T]

Nuclear receptor-binding factor 1 1.3.1.38
Bos taurus (Bovine). AAP45003.1
NP_858055.1
Q7YS70 [P]
Q7YS70.1

Probable trans-2-enoyl-CoA reductase, mitochondrial {ECO:0000313|EMBL:ACO10689.1} Caligus rogercresseyi (Sea louse). ACO10689.1

C1BNT6 [T]

Trans-2-enoyl-CoA reductase, mitochondrial isoform a {ECO:0000313|EMBL:JAB52157.1} Callithrix jacchus (White-tufted-ear marmoset).
XP_002750573.1
U3F3S7 [T]

Trans-2-enoyl-CoA reductase 2 1.3.1.10
1.3.1.38
Candida tropicalis (Yeast). AAL55471.1
AAL55472.1

Q8WZM3 [P]
Q8WZM3.1
Q8WZM4 [P]
Q8WZM4.1
1GU7
1GUF
1GYR
1H0K
1N9G
4W99
4WAS
Predicted protein {ECO:0000313|EMBL:EDP09833.1} Chlamydomonas reinhardtii (Chlamydomonas smithii). EDP09833.1
XP_001690095.1
A8HM32 [P]

Trans-2-enoyl-CoA reductase, mitochondrial 1.3.1.38
Danio rerio (Zebrafish) (Brachydanio rerio). AAH72704.1
AAI53449.1

A8E536
Q6GQN8 [T]
Q6GQN8.2

Uncharacterized protein {ECO:0000313|EMBL:AEE62583.1} Dendroctonus ponderosae (Mountain pine beetle). AEE62583.1

J3JWK3 [T]

FI19911p1 {ECO:0000313|EMBL:AFE85379.1} 1.3.1.38
Drosophila melanogaster (Fruit fly). AAF58322.2
AFE85379.1
AHN56194.1
NP_001286396.1
NP_610914.2
H8F4T6 [T]
Q9V6U9
Q9V6U9.2

AT25977p {ECO:0000313|EMBL:AAX51660.1} Drosophila melanogaster (Fruit fly). AAX51660.1

Q58CJ2 [T]

cDNA FLJ56723, highly similar to Trans-2-enoyl-CoA reductase, mitochondrial (EC 1.3.1.38) {ECO:0000313|EMBL:BAG62530.1} Homo sapiens (Human). BAG62530.1

B4DV18 [T]

Nuclear receptor-binding factor 1 1.3.1.38
Homo sapiens (Human). AAD34058.1
AAH01419.1
BAG52984.1
CAG32984.1
CAI14329.1
CAI14330.1
EAX07654.1
EAX07655.1
NP_001019903.2
NP_057095.3
Q9BV79 [P]
Q9BV79.2
1ZSY
2VCY
Trans-2-enoyl CoA reductase {ECO:0000313|EMBL:ACS32302.1} Jatropha curcas (Barbados nut). ACS32302.1

C5MRG3 [T]

NADPH quinone oxidoreductase {ECO:0000303|PubMed:14536026} 1.6.5.2 {ECO:0000269|PubMed:14536026}
Kluyveromyces marxianus (Yeast) (Candida kefyr). AAK77939.1

Q8NJJ9 [P]
Q8NJJ9.1

Uncharacterized protein {ECO:0000313|Ensembl:ENSMMUP00000020542} Macaca mulatta (Rhesus macaque). EHH14532.1
NP_001248098.1
F6RDJ9 [T]

Trans-2-enoyl-CoA reductase, mitochondrial 1.3.1.38
Mus musculus (Mouse). AAH03864.1
BAB22169.1
EDL30126.1
NP_079573.2
Q9DCS3 [P]
Q9DCS3.2

Zinc binding dehydrogenase {ECO:0000313|EMBL:BAM19614.1} Papilio xuthus (Asian swallowtail butterfly). BAM19614.1

I4DNX4 [T]

Putative uncharacterized protein {ECO:0000313|EMBL:ADE76581.1} Picea sitchensis (Sitka spruce) (Pinus sitchensis). ADE76581.1

D5AAL2 [T]

Putative uncharacterized protein {ECO:0000313|EMBL:ABK92727.1} Populus trichocarpa (Western balsam poplar) (Populus balsamifera subsp. trichocarpa). ABK92727.1

A9P8M4 [T]

Nuclear receptor-binding factor 1 1.3.1.38
Rattus norvegicus (Rat). BAA34804.1
NP_058905.1
Q9Z311 [P]
Q9Z311-1
Q9Z311.1

Trans-2-enoyl-CoA reductase 1.3.1.10
1.3.1.38
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). AAS56198.1
AHY74510.1
AJP37111.1
AJP82394.1
AJP82782.1
AJP83936.1
AJP87378.1
AJP87741.1
AJP88497.1
AJP88886.1
AJP90036.1
AJP91511.1
AJP91898.1
AJP92288.1
AJP92676.1
AJP93065.1
AJP93455.1
AJP93844.1
AJP94234.1
AJP94625.1
AJP95014.1
AJP95399.1
AJP95788.1
AJP96175.1
AJP97711.1
AJP99258.1
AJQ00416.1
AJQ00804.1
AJQ01189.1
AJQ01959.1
AJQ02347.1
AJQ03114.1
AJQ04994.1
AJQ05380.1
AJQ05766.1
AJQ06903.1
AJQ07286.1
AJQ08058.1
AJQ09600.1
AJQ09988.1
AJQ10375.1
AJQ13416.1
AJQ13803.1
BAA05651.1
CAA53683.1
CAA84968.1
CAY77809.1
DAA07148.1
EDN64641.1
EDV12070.1
EGA75894.1
EWG87612.1
EWG92398.1
EWG97621.1
EWH19442.1
NP_009582.1
A0A023Z907
A0A024XTL6
A0A024Y8W3
A6ZKX2
B3LNB7
C8Z420
E7K9Q9
P38071 [P]
W7PKY0
W7RE65

Trans-2-enoyl-CoA reductase (NADPH) {ECO:0000313|EMBL:CAX73582.1} 1.3.1.38 {ECO:0000313|EMBL:CAX73582.1}
Schistosoma japonicum (Blood fluke). CAX73582.1

C1LFV4 [T]

SJCHGC04006 protein {ECO:0000313|EMBL:AAX28351.2} Schistosoma japonicum (Blood fluke). AAX28351.2

Q5BW74 [T]

Trans-2-enoyl-CoA reductase, mitochondrial {ECO:0000250|UniProtKB:O43715} 1.3.1.38
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis). CAJ83709.1
NP_001016371.1
Q28GQ2 [T]
Q28GQ2.1

Uncharacterized protein {ECO:0000313|EMBL:ACR36399.1} Zea mays (Maize). ACR36399.1
NP_001183313.1
C4J5E9 [T]