ThYme: Thioester-active Enzymes

Family ER4

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Fold NAD(P)-binding Rossmann
Names of enzymes and/or genes present

Enoyl-ACP reductase
 

EC numbers

1.3.1.10 (Enoyl-ACP reductase)
 

Catalytic residues
Notes

1. ER domain of fatty acid synthase (FAS) and polyketide synthases (PKS)
2. Shares some sequences with KR4 (different domains)
 

Numbers [P] (Evidence at Protein Level) = 22
[T] (Evidence at Transcript Level) = 36
PDBs = 6
Bacteria
Sequence EC Number Organism GenBank ID RefSeq UniProt PDB
CurH {ECO:0000313|EMBL:AAT70103.1} Lyngbya majuscula. AAT70103.1

Q6DNE5 [P]

CurK {ECO:0000313|EMBL:AAT70106.1} Lyngbya majuscula. AAT70106.1

Q6DNE2 [P]

Zn-dependent oxidoreductase/polyketide synthase module {ECO:0000313|EMBL:EGJ28347.1} Moorea producens 3L. AEE88282.1
EGJ28347.1

F4Y428 [P]

Polyketide synthase module {ECO:0000313|EMBL:EGJ28344.1} Moorea producens 3L. AEE88279.1
EGJ28344.1

F4Y425 [P]

Mycocerosic acid synthase 2.3.1.111
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97). AAA25369.1
AET20228.1
AGE68955.1
AHM08697.1
AIR48157.1
BAH27235.1
CAL72951.1
CCC65539.1
CDO44232.1
ESK70797.1
ESK74486.1
KEC51273.1
KEY07874.1
KEY08901.1
KFW14380.1
KFW15803.1
KFW16469.1
KFW25805.1
KFW27152.1
KFW29572.1
KFW40871.1
KFW50539.1
KFW50949.1
KFW52388.1
KIU59692.1
KIX88515.1
NP_856610.1
A0A083VUZ5
A1KMT5
C1AG56
F9UX12
Q02251 [P]
Q02251.2

Phenolpthiocerol synthesis type-I polyketide synthase PpsC {ECO:0000313|EMBL:KBN11053.1} 2.3.1.41
2.3.1.41 {ECO:0000313|EMBL:KFC55694.1}
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97). CCC65532.1
CDO44225.1
NP_856603.1
F9UX05
Q7TXL8 [P]

Probable polyketide synthase pks1 {ECO:0000313|EMBL:CCC65545.1} 2.3.1.41
Mycobacterium bovis BCG str. Moreau RDJ. AET20234.1
AGE68963.1
BAH27241.1
CAL72957.1
CCC65545.1
CDO44238.1
ESK74491.1
KEC51266.1
KEY07880.1
KEY08646.1
KEY08907.1
NP_856616.1
WP_010950804.1
A1KMU1
C1AG62
F9UXI5
Q7TXK8 [P]
Q7TXK8.1

Beta-ketoacyl-acyl-carrier-protein synthase I 2.3.1.41
Mycobacterium marinum (strain ATCC BAA-535 / M). ACC40211.1
WP_012393570.1
YP_001850066.1
B2HIL7 [P]
B2HIL7.1

Polyketide synthase {ECO:0000313|EMBL:KEY06338.1} 2.3.1.-
Mycobacterium tuberculosis MD15956. AAK48300.1
ABQ75654.1
AII92414.1
CCP46654.1
KAQ13909.1
KBJ91617.1
KBN09154.1
KBN09627.1
KHS04980.1
NP_218342.1
NP_338486.1
YP_001285216.1
YP_006517322.1
A0A040DBV8
A0A045H861
A0A046QSP7
A0A047RPB5
A0A047RQI8
A5U9F4
P9WQE8
P9WQE9 [P]

Polyketide synthase Pks1 {ECO:0000313|EMBL:KBN11065.1} Mycobacterium tuberculosis OFXR-28. ABQ74754.1
ABR07287.1
AEJ51507.1
AEN01410.1
AFN50928.1
AHJ56188.1
AIB49645.1
AJF04308.1
BAL67008.1
BAQ07093.1
CCG12829.1
CCP45750.1
EGB27591.1
KAK92702.1
KAK98929.1
KAL11218.1
KAL15713.1
KAL20073.1
KAL22028.1
KAL26469.1
KAL31633.1
KAL36645.1
KAL39254.1
KAL41921.1
KAL45930.1
KAL51309.1
KAL52396.1
KAL58183.1
KAL64073.1
KAL65080.1
KAL75233.1
KAL77652.1
KAL82766.1
KAL85180.1
KAL90902.1
KAL95280.1
KAM06553.1
KAM19283.1
KAM24908.1
KAM26306.1
KAM29105.1
KAM34016.1
KAM37388.1
KAM38168.1
KAM48246.1
KAM55381.1
KAM60877.1
KAM65314.1
KAM67411.1
KAM71336.1
KAM78486.1
KAM79852.1
KAM83354.1
KAM89014.1
KAM91519.1
KAM94887.1
KAN00915.1
KAN03801.1
KAN06220.1
KAN09122.1
KAN17355.1
KAN18847.1
KAN22639.1
KAN29325.1
KAN32715.1
KAN33676.1
KAN42042.1
KAN43110.1
KAN47058.1
KAN51467.1
KAN58439.1
KAN60030.1
KAN65503.1
KAN68938.1
KAN72901.1
KAN73718.1
KAN78582.1
KAN84665.1
KAN88858.1
KAN97186.1
KAO01239.1
KAO10938.1
KAO18659.1
KAO20838.1
KAO22942.1
KAO35268.1
KAO47640.1
KAO55233.1
KAO59620.1
KAO65612.1
KAO66351.1
KAO71654.1
KAO75103.1
KAO79927.1
KAO82956.1
KAO87950.1
KAO90521.1
KAP00327.1
KAP02326.1
KAP09354.1
KAP12128.1
KAP15459.1
KAP19226.1
KAP20758.1
KAP27624.1
KAP32131.1
KAP36039.1
KAP39497.1
KAP47651.1
KAP50189.1
KAP51742.1
KAP58780.1
KAP64208.1
KAP73121.1
KAP75681.1
KAP80830.1
KAP84582.1
KAP87129.1
KAP90610.1
KAP97445.1
KAP99352.1
KAQ05434.1
KAQ15038.1
KAQ21968.1
KAQ27800.1
KAQ30808.1
KAQ34636.1
KAQ42337.1
KAQ45340.1
KAQ50453.1
KAQ59486.1
KAQ59581.1
KAQ61529.1
KAQ64800.1
KAQ67814.1
KAQ73936.1
KAQ80767.1
KAQ81696.1
KAQ86680.1
KAQ91019.1
KAQ93571.1
KAQ98169.1
KAR03054.1
KAR06603.1
KAR11664.1
KAR16180.1
KAR23991.1
KAR25484.1
KAR32813.1
KAR36150.1
KAR42377.1
KAR47793.1
KAR50329.1
KAR59592.1
KAR62602.1
KAR71969.1
KAR75802.1
KAR75902.1
KAR84030.1
KAR87074.1
KAR87556.1
KAS00192.1
KAS09819.1
KAS10694.1
KAS15407.1
KAS22691.1
KAS25131.1
KAS33390.1
KAS42341.1
KAS44998.1
KAS51002.1
KAS56334.1
KAS63091.1
KAS64113.1
KAS74587.1
KAS80190.1
KAS83868.1
KAS88844.1
KAT03014.1
KAT06048.1
KAT15957.1
KAT20763.1
KAT21863.1
KAT28939.1
KAT29251.1
KAT33833.1
KAT38210.1
KAT47574.1
KAT47784.1
KAT49642.1
KAT50159.1
KAT58819.1
KAT71837.1
KAT73581.1
KAT74710.1
KAT83907.1
KAT86907.1
KAT89963.1
KAT95284.1
KAU02224.1
KAU08104.1
KAU15750.1
KAU17567.1
KAU19866.1
KAU33756.1
KAU35275.1
KAU37796.1
KAU45723.1
KAU48503.1
KAU55300.1
KAU56120.1
KAU58274.1
KAU66348.1
KAU71775.1
KAU78741.1
KAU85454.1
KAU85646.1
KAU91821.1
KAU94621.1
KAV03053.1
KAV10232.1
KAV11120.1
KAV16662.1
KAV28681.1
KAV30768.1
KAV34102.1
KAV37735.1
KAV42026.1
KAV50907.1
KAV54246.1
KAV58937.1
KAV66439.1
KAV75358.1
KAV80756.1
KAV84003.1
KAV86575.1
KAV91944.1
KAW03789.1
KAW07891.1
KAW14969.1
KAW15646.1
KAW26249.1
KAW38967.1
KAW39907.1
KAW45851.1
KAW50998.1
KAW53384.1
KAW61186.1
KAW65741.1
KAW70970.1
KAW78134.1
KAW84661.1
KAW87422.1
KAW92128.1
KAX65185.1
KAY15905.1
KAY46443.1
KAY58489.1
KAY71160.1
KAZ04541.1
KAZ24184.1
KAZ45238.1
KBA11836.1
KBA43525.1
KBA53049.1
KBA60288.1
KBA73587.1
KBA80308.1
KBA89633.1
KBA96700.1
KBB09293.1
KBB12479.1
KBB15818.1
KBB23953.1
KBB28642.1
KBB35548.1
KBB45187.1
KBB47067.1
KBB60279.1
KBB70052.1
KBB72050.1
KBB88916.1
KBC21654.1
KBC33145.1
KBC36441.1
KBC39617.1
KBC56012.1
KBC57352.1
KBC63127.1
KBC91681.1
KBD07795.1
KBD27564.1
KBD43627.1
KBD47176.1
KBD67278.1
KBD75101.1
KBD83774.1
KBD94096.1
KBD98323.1
KBE02548.1
KBE06850.1
KBE21295.1
KBE26772.1
KBE31274.1
KBE47109.1
KBE51075.1
KBE59352.1
KBF33479.1
KBF50212.1
KBF61296.1
KBF69911.1
KBF77427.1
KBG07655.1
KBG17171.1
KBG21689.1
KBG40756.1
KBG70410.1
KBG76044.1
KBG80267.1
KBG86173.1
KBH29657.1
KBH31175.1
KBH45001.1
KBH99728.1
KBH99873.1
KBI09673.1
KBI33967.1
KBI38440.1
KBI48736.1
KBI70093.1
KBJ00172.1
KBJ25141.1
KBJ29862.1
KBJ33960.1
KBJ50116.1
KBJ64025.1
KBJ66737.1
KBJ67885.1
KBJ76211.1
KBJ90040.1
KBJ93118.1
KBJ97972.1
KBK05216.1
KBK06093.1
KBK10576.1
KBK14390.1
KBK20874.1
KBK29229.1
KBK29439.1
KBK38941.1
KBK39309.1
KBK41517.1
KBK44934.1
KBK45695.1
KBK59015.1
KBK59638.1
KBK69037.1
KBK69343.1
KBK75232.1
KBK76391.1
KBK83841.1
KBK87179.1
KBK92572.1
KBK98718.1
KBL02188.1
KBL09132.1
KBL14251.1
KBL15660.1
KBL16354.1
KBL21097.1
KBL26707.1
KBL30931.1
KBL42190.1
KBL44213.1
KBL47604.1
KBL50839.1
KBL51114.1
KBL57363.1
KBL61692.1
KBL72769.1
KBL75594.1
KBL79441.1
KBL86446.1
KBL90354.1
KBL92786.1
KBL98346.1
KBM02759.1
KBM10666.1
KBM11675.1
KBM16911.1
KBM25000.1
KBM29197.1
KBM30942.1
KBM37792.1
KBM40384.1
KBM45057.1
KBM46526.1
KBM48592.1
KBM61304.1
KBM64378.1
KBM66388.1
KBM70668.1
KBM76275.1
KBM81059.1
KBM85366.1
KBM86792.1
KBM91828.1
KBM93544.1
KBN02311.1
KBN03210.1
KBN09870.1
KBN11065.1
KBN19655.1
KBN25752.1
KBN27317.1
KBN29874.1
KBN35782.1
KBO36267.1
KBO39707.1
KBO40094.1
KBO61613.1
KBO89326.1
KBO97272.1
KBP36565.1
KBP62664.1
KBP64617.1
KBP67201.1
KBP71891.1
KBP72090.1
KBP79398.1
KBP84227.1
KBP84330.1
KBP88750.1
KBP92614.1
KBP98081.1
KBQ03047.1
KBQ07060.1
KBQ12447.1
KBQ17270.1
KBQ21898.1
KBQ23393.1
KBQ32007.1
KBQ33556.1
KBQ41851.1
KBQ43071.1
KBQ46623.1
KBQ51878.1
KBQ53299.1
KBQ57831.1
KBQ59835.1
KBQ67220.1
KBQ74789.1
KBQ78019.1
KBQ81076.1
KBQ84595.1
KBQ93789.1
KBQ95141.1
KBQ99612.1
KBR08239.1
KBR14404.1
KBR15019.1
KBR16841.1
KBR24002.1
KBR26253.1
KBR32393.1
KBR35251.1
KBR36394.1
KBR49362.1
KBR57517.1
KBR66541.1
KBR77510.1
KBR90203.1
KBR96833.1
KBR98264.1
KBR98974.1
KBS12183.1
KBS14088.1
KBS25449.1
KBS27080.1
KBS27470.1
KBS32759.1
KBS42115.1
KBS46968.1
KBS56089.1
KBS57590.1
KBS58395.1
KBS63954.1
KBS69865.1
KBS72706.1
KBS80573.1
KBS80839.1
KBS86542.1
KBS89869.1
KBS94346.1
KBS95157.1
KBT01341.1
KBT07888.1
KBT10549.1
KBT15619.1
KBT19741.1
KBT23942.1
KBT27073.1
KBT30008.1
KBT35128.1
KBT38583.1
KBT42074.1
KBT45508.1
KBT49081.1
KBT51347.1
KBT59607.1
KBT62042.1
KBT62665.1
KBT73368.1
KBT81442.1
KBT82127.1
KBT91930.1
KBT93373.1
KBT94283.1
KBU01696.1
KBU04379.1
KBU05862.1
KBU13120.1
KBU17350.1
KBU19354.1
KBU22069.1
KBU29530.1
KBU34251.1
KBU39456.1
KBU45148.1
KBU51777.1
KBU54365.1
KBU65673.1
KBU70523.1
KBU70963.1
KBU75128.1
KBU78891.1
KBU86136.1
KBU87832.1
KBU88656.1
KBU97562.1
KBU98913.1
KBV05828.1
KBV08347.1
KBV09670.1
KBV13608.1
KBV18896.1
KBV23655.1
KBV28042.1
KBV28876.1
KBV34468.1
KBV37667.1
KBV38610.1
KBV48286.1
KBV54039.1
KBV56629.1
KBV61253.1
KBV74362.1
KBV77146.1
KBV78679.1
KBV88818.1
KBV92559.1
KBV96001.1
KBV99551.1
KBW04611.1
KBW10429.1
KBW14424.1
KBW21065.1
KBW22349.1
KBW23500.1
KBW26804.1
KBW30101.1
KBW33410.1
KBW36719.1
KBW41524.1
KBW49676.1
KBW63358.1
KBW64967.1
KBW65289.1
KBW69600.1
KBW70811.1
KBW73338.1
KBW81604.1
KBW85273.1
KBW89482.1
KBW94917.1
KBX02935.1
KBX05718.1
KBX05930.1
KBX09135.1
KBX20116.1
KBX20391.1
KBX22267.1
KBX27448.1
KBX35232.1
KBX40293.1
KBX46170.1
KBX47842.1
KBX52565.1
KBX52725.1
KBX54180.1
KBX60385.1
KBX70667.1
KBX77145.1
KBX79648.1
KBX90313.1
KBX98242.1
KBY08931.1
KBY11973.1
KBY15515.1
KBY22366.1
KBY27378.1
KBY34847.1
KBY38189.1
KBY39862.1
KBY44036.1
KBY50247.1
KBY52401.1
KBY55833.1
KBY67683.1
KBY72865.1
KBY73075.1
KBY79116.1
KBY86144.1
KBY94107.1
KBY94255.1
KBZ00647.1
KBZ04696.1
KBZ06354.1
KBZ18202.1
KBZ23577.1
KBZ24149.1
KBZ32920.1
KBZ34789.1
KBZ47463.1
KBZ48197.1
KBZ50844.1
KBZ51883.1
KBZ64138.1
KBZ65665.1
KBZ73516.1
KBZ82566.1
KBZ94546.1
KBZ96490.1
KCA04096.1
KCA08266.1
KCA10322.1
KCA11975.1
KCA22308.1
KCA26063.1
KCA30562.1
KCA39778.1
KCA42722.1
KCA46437.1
KCA54088.1
KCA59073.1
KCA66258.1
KCA76505.1
KCA78833.1
KCA78993.1
KCA88776.1
KCA90710.1
KCA92889.1
KCB00938.1
KCB02113.1
KCB04622.1
KCB09983.1
KCB14975.1
KCB54356.1
KCB62815.1
KCB68471.1
KCB75857.1
KCB83139.1
KCB83206.1
KCB90148.1
KCB94663.1
KCB99632.1
KCC00135.1
KCC04189.1
KCC09030.1
KCC12508.1
KCC19139.1
KCC20073.1
KCC24473.1
KCC28470.1
KCC35684.1
KCC39238.1
KCC46423.1
KCC47649.1
KCC53430.1
KCC55241.1
KCC60502.1
KCC63767.1
KCC70358.1
KCC74225.1
KCC79315.1
KCC83947.1
KCC84156.1
KCC90151.1
KCC97251.1
KCC98326.1
KCD03112.1
KCD03881.1
KCD11516.1
KCD11990.1
KCD18329.1
KCD22608.1
KCD24559.1
KCD30686.1
KCD37307.1
KCD51155.1
KCD53647.1
KCD57124.1
KCD62408.1
KCD66938.1
KCD74263.1
KCD84920.1
KCD87179.1
KCD89396.1
KCD94323.1
KCE10378.1
KCE14063.1
KCE26353.1
KCE28126.1
KCE34581.1
KCE43003.1
KCE46350.1
KCE48387.1
KCE55131.1
KCE63808.1
KCE63964.1
KCE70809.1
KCE78038.1
KCE80180.1
KCE86503.1
KCE88882.1
KCE94071.1
KCE96860.1
KCF02042.1
KCF06835.1
KCF09505.1
KCF15136.1
KCF15508.1
KCF22975.1
KCF31942.1
KCF36013.1
KCF40494.1
KCF44430.1
KCF47194.1
KCF51121.1
KCF62217.1
KCF68405.1
KCF72401.1
KCF75323.1
KCF83505.1
KCF90541.1
KCF96374.1
KCF97165.1
KCG02610.1
KCG03770.1
KCG12866.1
KCG20140.1
KCG21570.1
KCG29516.1
KCG31401.1
KCG35722.1
KCG37202.1
KCG42596.1
KCG45293.1
KCG49340.1
KCG66266.1
KCG70298.1
KCG87615.1
KCG93178.1
KCG95634.1
KCH02492.1
KCH08378.1
KCH11480.1
KCH17892.1
KCH22124.1
KCH27118.1
KCH28739.1
KCH34704.1
KCH35230.1
KCH43482.1
KCH47541.1
KCH49759.1
KCH57645.1
KCH61078.1
KCH65826.1
KCH68160.1
KCH73672.1
KCH75695.1
KCH82757.1
KCH88924.1
KCH94703.1
KCH95978.1
KCH98012.1
KCI00034.1
KCI06778.1
KCI07689.1
KCI12703.1
KCI21095.1
KCI23298.1
KCI28417.1
KCI28631.1
KCI33633.1
KCI35539.1
KCI40815.1
KCI47000.1
KCI51249.1
KCI55912.1
KCI58317.1
KCI64330.1
KCI66529.1
KCI70962.1
KCI76162.1
KCI76374.1
KCI81426.1
KCI86470.1
KCI88614.1
KCI94172.1
KCI99783.1
KCJ02484.1
KCJ06388.1
KCJ11213.1
KCJ11695.1
KCJ19830.1
KCJ27184.1
KCJ29002.1
KCJ29470.1
KCJ33360.1
KCJ38802.1
KCJ42717.1
KCJ49198.1
KCJ51256.1
KCJ61735.1
KCJ68456.1
KCJ71607.1
KCJ74023.1
KCJ76380.1
KCJ82802.1
KCJ87432.1
KCJ90714.1
KCJ92132.1
KCJ96557.1
KCK04163.1
KCK08075.1
KCK22437.1
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NP_217462.1
WP_003917711.1
YP_006516399.1
A0A047RSJ3
A0A047RVZ5
A0A056EME9
A0A056FRB0
A5U6V4
A5WRJ8
H8EWC9
I6Y235
P96285 [P]
P96285.4

Phenolpthiocerol synthesis type-I polyketide synthase PpsC {ECO:0000313|EMBL:KBN11053.1} 2.3.1.41
2.3.1.41 {ECO:0000313|EMBL:KFC55694.1}
Mycobacterium tuberculosis OFXR-28. ABQ74740.1
ABR07274.1
AEJ47883.1
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KCE14051.1
KCE17483.1
KCE21133.1
KCE26341.1
KCE34569.1
KCE35335.1
KCE54961.1
KCE55119.1
KCE63952.1
KCE72077.1
KCE78026.1
KCE94059.1
KCE96848.1
KCF02030.1
KCF06823.1
KCF09493.1
KCF15124.1
KCF15496.1
KCF22963.1
KCF23955.1
KCF31930.1
KCF36001.1
KCF44418.1
KCF47182.1
KCF51109.1
KCF55895.1
KCF56280.1
KCF62205.1
KCF72389.1
KCF75311.1
KCF77301.1
KCF83493.1
KCF90529.1
KCF96386.1
KCF97153.1
KCG02598.1
KCG03758.1
KCG10853.1
KCG12854.1
KCG21558.1
KCG35710.1
KCG37189.1
KCG42584.1
KCG45281.1
KCG49328.1
KCG57110.1
KCG60354.1
KCG65003.1
KCG66278.1
KCG70286.1
KCG71589.1
KCG80876.1
KCG87392.1
KCG95622.1
KCH08390.1
KCH11468.1
KCH12100.1
KCH22112.1
KCH28727.1
KCH34692.1
KCH35218.1
KCH43470.1
KCH47529.1
KCH49747.1
KCH54964.1
KCH57633.1
KCH61066.1
KCH65814.1
KCH68148.1
KCH73660.1
KCH82745.1
KCH88912.1
KCH95990.1
KCH98000.1
KCI00022.1
KCI06766.1
KCI07677.1
KCI23286.1
KCI28405.1
KCI33621.1
KCI35527.1
KCI40803.1
KCI55900.1
KCI64318.1
KCI66517.1
KCI70950.1
KCI76150.1
KCI76362.1
KCI81414.1
KCI86458.1
KCI94160.1
KCJ02472.1
KCJ11201.1
KCJ28990.1
KCJ29458.1
KCJ33348.1
KCJ38790.1
KCJ42705.1
KCJ49186.1
KCJ51244.1
KCJ55202.1
KCJ57544.1
KCJ61723.1
KCJ68444.1
KCJ71595.1
KCJ74011.1
KCJ76368.1
KCK27010.1
KCK28762.1
KCK34819.1
KCK38932.1
KCK42220.1
KCK49735.1
KCK55683.1
KCK55914.1
KCK64661.1
KCK67704.1
KCK70051.1
KCK75970.1
KCK77197.1
KCK84568.1
KCK85092.1
KCK93024.1
KCK93634.1
KCL00555.1
KCL03721.1
KCL12130.1
KCL24417.1
KCL40410.1
KCL42072.1
KCL46653.1
KCL47513.1
KCL70099.1
KCL75471.1
KCL78673.1
KCL86280.1
KCL88467.1
KCL92748.1
KCM10633.1
KCM16086.1
KCM26302.1
KCM28856.1
KCM34033.1
KCM34759.1
KCM42511.1
KCM50953.1
KCM54855.1
KCM63866.1
KCM66077.1
KCM70132.1
KCM72020.1
KCM79102.1
KCM79305.1
KCM87720.1
KCM94685.1
KCM95783.1
KCN02479.1
KCN05387.1
KCN12088.1
KCN13686.1
KCN18588.1
KCN26615.1
KCN31193.1
KCN36060.1
KCN42241.1
KCN46349.1
KCN50770.1
KCN54471.1
KCN62094.1
KCN77281.1
KCN84777.1
KCN86157.1
KCN91835.1
KCN97008.1
KCO12442.1
KCO28860.1
KCO30098.1
KCO37783.1
KCO38030.1
KCO43652.1
KCO51372.1
KCO56541.1
KCO66321.1
KCO70994.1
KCO75874.1
KCO93680.1
KCO94928.1
KCO99824.1
KCP06611.1
KCP09345.1
KCP11399.1
KCP15334.1
KCP18545.1
KCP23066.1
KCP27093.1
KCP31807.1
KCP33892.1
KCP39712.1
KCP43878.1
KCP51457.1
KCP54084.1
KCP62517.1
KCP71735.1
KCP78611.1
KCP83754.1
KCP85357.1
KCP98965.1
KCP99510.1
KCQ09718.1
KCQ12552.1
KCQ15385.1
KCQ24149.1
KCQ25669.1
KCQ31138.1
KCQ38429.1
KCQ42969.1
KCQ51406.1
KCQ59267.1
KCQ62029.1
KCQ71369.1
KCQ80709.1
KCQ87924.1
KCQ99426.1
KCR03619.1
KCR05353.1
KCR13468.1
KCR17582.1
KCR27740.1
KCR28854.1
KCR39234.1
KCR42284.1
KCR47543.1
KCR61859.1
KCR62486.1
KCR65753.1
KCR71427.1
KCR78911.1
KCR82911.1
KCR85945.1
KCR94491.1
KCR95190.1
KCS00285.1
KCS06655.1
KCS13205.1
KCS13335.1
KCS19256.1
KCS25312.1
KCS29197.1
KCS30427.1
KCS33319.1
KCS40199.1
KCS45001.1
KCS45779.1
KCS49714.1
KCS57711.1
KCS60630.1
KCS73727.1
KCS74505.1
KCS81116.1
KCS87800.1
KCS88493.1
KCS95823.1
KCS96872.1
KCT07509.1
KCT11652.1
KCT17872.1
KCT24252.1
KCT24642.1
KCT34860.1
KCT37568.1
KCT44469.1
KCT45281.1
KCT50460.1
KCT55555.1
KCT66103.1
KCT68706.1
KCT72053.1
KCT74465.1
KCT79965.1
KCT82650.1
KCT87694.1
KCT89419.1
KCT95075.1
KCU03619.1
KCU07486.1
KCU08613.1
KCU17823.1
KCU24685.1
KCU25224.1
KCU35231.1
KCU44456.1
KCU53092.1
KCU60691.1
KCU65714.1
KCU71674.1
KCU77942.1
KCU82180.1
KCU85924.1
KDM95202.1
KEA68698.1
KEA70702.1
KEA79134.1
KEA81025.1
KEA86049.1
KEA92222.1
KEA95525.1
KEB01560.1
KEB03725.1
KEB09122.1
KEB13138.1
KEB15088.1
KEB20064.1
KEB20687.1
KEB26976.1
KEB33395.1
KEB33533.1
KEB39490.1
KEB51795.1
KEB53202.1
KEB58554.1
KEB59480.1
KEB65929.1
KEB69568.1
KEB72545.1
KEB81405.1
KEC17616.1
KEC29569.1
KEC32156.1
KEC38262.1
KEC38359.1
KEC43218.1
KEC44891.1
KEC51280.1
KED06461.1
KEP58745.1
KEY08894.1
KFC55694.1
KFE92576.1
KFL39145.1
KFW37560.1
KFW39860.1
KFZ73349.1
KIN22538.1
KIU59686.1
KIX88509.1
NP_217449.1
WP_003414837.1
YP_006516387.1
A0A042R4F6
A0A045IDF5
A0A046R1D3
A0A047RUL6
A0A056FRL7
A0A0B6SZC4
A1KMS8
A5U6U0
A5WRI5
C1AG49
D6FKG8
I6X5S4
P96202 [P]
P96202.2
Q7TXL8.1
1PQW
ORF 2 2.3.1.94
Saccharopolyspora erythraea (Streptomyces erythraeus). AAA26494.1
CAA44448.1

Q03132 [P]
Q03132.3

Polyketide synthase extender module 2 {ECO:0000313|EMBL:AAG23265.1} Saccharopolyspora spinosa. AAG23265.1

Q9ALM5 [P]
3SLK
Tautomycetin biosynthetic PKS {ECO:0000313|EMBL:ABI94380.1} Streptomyces sp. CK4412. ABI94380.1

A4KCE5 [P]

Type I polyketide synthase PikAII {ECO:0000313|EMBL:AAC69330.1} Streptomyces venezuelae. AAC69330.1

Q9ZGI4 [P]

Eukaryota
Sequence EC Number Organism GenBank ID RefSeq UniProt PDB
Polyketide synthase SteelyB {ECO:0000313|EMBL:BAP16677.1} Acytostelium subglobosum. BAP16677.1
GAM17140.1

A0A077JCW3 [T]

Fatty acid synthase {ECO:0000313|EMBL:AGR49310.1} Agrotis ipsilon (Black cutworm moth). AGR49310.1

U5KGX9 [T]

Fatty acid synthase {ECO:0000313|EMBL:AID66645.1} Agrotis segetum (turnip moth). AID66645.1

A0A068FRC8 [T]

Lovastatin diketide synthase LovF 2.3.1.-
Aspergillus terreus. AAD34559.1

Q9Y7D5 [P]
Q9Y7D5.1

Fatty acid synthase {ECO:0000313|EMBL:AEY83835.1} 2.3.1.85 {ECO:0000313|EMBL:AEY83835.1}
Bombus lucorum (White-tailed bumblebee). AEY83835.1

H6WCY9 [T]

Fatty acid synthase {ECO:0000313|EMBL:AEW43642.1} 2.3.1.85 {ECO:0000313|EMBL:AEW43642.1}
Bombus terrestris (Buff-tailed bumblebee) (Apis terrestris). AEW43642.1
NP_001267840.1
G9JWG5 [T]

P270 {ECO:0000313|EMBL:AAB53258.1} Bombyx mori (Silk moth). AAB53258.1
NP_001037478.1
O01678 [T]

P260 {ECO:0000313|EMBL:AAB53257.1} Bombyx mori (Silk moth). AAB53257.1
NP_001037476.1
O01677 [T]

Oleoyl-[acyl-carrier-protein] hydrolase 1.1.1.100
1.3.1.39
2.3.1.38
2.3.1.39
2.3.1.41
2.3.1.85
3.1.2.14
4.2.1.59
Bos taurus (Bovine). AAR17600.1
AAR19788.1
NP_001012687.1
Q71SP7 [T]
Q71SP7.1

Fatty acid synthase {ECO:0000313|EMBL:ABB36643.1} Capra hircus (Goat). ABB36643.1

Q076H7 [T]

Fatty acid synthase {ECO:0000313|EMBL:ABI95140.2} Capra hircus (Goat). ABI95140.2
NP_001272558.1
Q06B57 [T]

Fatty acid synthase {ECO:0000313|EMBL:JAB92698.1} Ceratitis capitata (Mediterranean fruit fly) (Tephritis capitata).
XP_004524715.1
XP_004524716.1
W8B6N0 [T]

Putative fatty acid synthase 1 {ECO:0000313|EMBL:AHL67652.1} Chilo suppressalis (striped riceborer). AHL67652.1

W8R9W4 [T]

Type I polyketide synthase {ECO:0000313|EMBL:EDP07994.1} Chlamydomonas reinhardtii (Chlamydomonas smithii). EDP07994.1
XP_001698501.1
A8HZR1 [P]

Steely2 2.3.1.-
2.3.1.74
Dictyostelium discoideum (Slime mold). EAL62021.1
XP_635518.1
Q54FI3 [T]
Q54FI3.1

Probable polyketide synthase 16 2.3.1.-
Dictyostelium discoideum (Slime mold). EAL69815.1
XP_643784.1
Q869W9 [T]
Q869W9.1

Probable polyketide synthase 18 2.3.1.-
Dictyostelium discoideum (Slime mold). EAL66719.1
XP_640701.1
Q54TW0 [T]
Q54TW0.1

GH02912p {ECO:0000313|EMBL:AAM52599.1} Drosophila melanogaster (Fruit fly). AAM52599.1

Q8MR70 [T]

V(2)k05816, isoform A {ECO:0000313|EMBL:AAF51149.1} 1.-.-.- {ECO:0000313|EMBL:AAF51149.1}
2.3.1.38 {ECO:0000313|EMBL:AAF51149.1}
2.3.1.39 {ECO:0000313|EMBL:AAF51149.1}
2.3.1.41 {ECO:0000313|EMBL:AAF51149.1}
3.1.-.- {ECO:0000313|EMBL:AAF51149.1}
Drosophila melanogaster (Fruit fly). AAF51149.1
ACZ67868.1
NP_647613.1
Q9VQL6 [T]

BcDNA.GH07626 {ECO:0000313|EMBL:AAD38618.1} Drosophila melanogaster (Fruit fly). AAD38618.1

Q7KML1 [T]

MIP15305p {ECO:0000313|EMBL:ADB57067.1} Drosophila melanogaster (Fruit fly). ADB57067.1

D2NUK3 [T]

FI15913p1 {ECO:0000313|EMBL:AET14856.1} Drosophila melanogaster (Fruit fly). AET14856.1

G7H848 [T]

Oleoyl-[acyl-carrier-protein] hydrolase 1.1.1.100
1.3.1.39
2.3.1.38
2.3.1.39
2.3.1.41
2.3.1.85
3.1.2.14
4.2.1.59
Gallus gallus (Chicken). AAA48767.1
AAA82106.1
AAB46389.1

P12276 [P]
P12276.5

FASN protein {ECO:0000313|EMBL:AAH14631.1} Homo sapiens (Human). AAH14631.1

Q6PJJ3 [T]

Oleoyl-[acyl-carrier-protein] hydrolase 1.1.1.100
1.3.1.39
2.3.1.38
2.3.1.39
2.3.1.41
2.3.1.85
3.1.2.14
4.2.1.59
Homo sapiens (Human). AAA73576.1
AAB35516.1
AAC50259.1
AAH07267.1
AAH07909.1
AAH14634.2
AAH63242.1
AAS09886.1
BAE06070.1
BAG10519.1
NP_004095.4
XP_011521840.1
P49327 [P]
P49327.3
4W82
4W9N
Predicted protein {ECO:0000313|EMBL:BAK02865.1} Hordeum vulgare var. distichum (Domesticated barley). BAK02865.1

F2E693 [T]

Fatty acid synthase {ECO:0000313|EMBL:ADM88556.1} Litopenaeus vannamei (Whiteleg shrimp) (Penaeus vannamei). ADM88556.1

F8RHR0 [T]

Oleoyl-[acyl-carrier-protein] hydrolase 1.1.1.100
1.3.1.39
2.3.1.38
2.3.1.39
2.3.1.41
2.3.1.85
3.1.2.14
4.2.1.59
Mus musculus (Mouse). AAG02285.1
AAH46513.1
AAH59850.1
BAC37895.1
CAA31525.1
CAM27545.1
NP_032014.3
P19096 [P]
P19096.2

cDNA clone:006-307-G03, full insert sequence {ECO:0000313|EMBL:BAG96812.1} Oryza sativa subsp. japonica (Rice). BAD19379.1
BAD19427.1
BAF10356.1
BAG87149.1
BAG96812.1
EEE58007.1
NP_001048442.1
Q6K840 [T]

Fatty acid synthase {ECO:0000313|EMBL:AAL86892.1} Ovis aries (Sheep). AAL86892.1

Q8SPG4 [T]

Polyketide synthase {ECO:0000313|EMBL:BAM77409.1} Penicillium purpurogenum (Soft rot fungus) (Talaromyces purpurogenus). BAM77409.1

L8B2L5 [T]

Polyketide synthase {ECO:0000313|EMBL:AAR85531.1} Peyronellaea zeae-maydis. AAR85531.1

Q6RKG3 [T]

Type I polyketide synthase {ECO:0000313|EMBL:AAO62426.1} Phoma sp. C2932. AAO62426.1

Q86ZD9 [T]

Putative uncharacterized protein {ECO:0000313|EMBL:ABK23274.1} Picea sitchensis (Sitka spruce) (Pinus sitchensis). ABK23274.1
ABK23700.1
ACN40398.1

A9NRL3 [T]

Oleoyl-[acyl-carrier-protein] hydrolase 1.1.1.100
1.3.1.39
2.3.1.38
2.3.1.39
2.3.1.41
2.3.1.85
3.1.2.14
4.2.1.59
Rattus norvegicus (Rat). AAA41144.1
AAA41145.1
AAA57219.1
CAA31780.1
CAA31882.1
CAA44679.1
CAA44680.1
EDM06909.1
NP_059028.1
P12785 [P]
P12785.3

Fatty acid synthase {ECO:0000313|EMBL:AAX55638.1} Sus scrofa (Pig). AAX55638.1

Q58G70 [T]

Fatty acid synthase {ECO:0000313|EMBL:ABR09275.1} Sus scrofa (Pig). ABR09275.1
NP_001093400.1
A5YV76 [P]
2VZ8
2VZ9
Fatty acid synthase {ECO:0000313|EMBL:AAX51683.1} Sus scrofa (Pig). AAX51683.1

Q58GK8 [T]

Type I polyketide synthase PKS8 {ECO:0000313|EMBL:AGI60159.1} Usnea longissima. AGI60159.1

S4UF59 [T]

Reducing polyketide synthase {ECO:0000313|EMBL:AEJ54468.1} Usnea longissima. AEJ54468.1
AEJ54469.1

G0YSV9 [T]

Uncharacterized protein {ECO:0000313|EMBL:ACF85182.1, ECO:0000313|EnsemblPlants:GRMZM2G008728_P03} Zea mays (Maize). ACF85182.1
AFW73932.1

B4FST9 [T]

Uncharacterized protein {ECO:0000313|EMBL:ACF79357.1} Zea mays (Maize). ACF79357.1

B4FB64 [T]

Uncharacterized protein {ECO:0000313|EMBL:ACF80794.1, ECO:0000313|EnsemblPlants:GRMZM2G008728_P02} Zea mays (Maize). ACF80794.1
ACG38076.1
ACG39863.1
AFW73931.1
NP_001150639.1
B4FFA1 [T]