ThYme: Thioester-active Enzymes

Family HD6

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Names of enzymes and/or genes present

FabZ
Hydroxymyristoyl-ACP dehydratases
Hydroxyacyl-ACP dehydratase

EC numbers

4.2.1.- (Unclassified hydro-lyases)
4.2.1.60 (3-hydroxydecanoyl-ACP dehydratases)

Catalytic residues
Notes
Numbers [P] (Evidence at Protein Level) = 11
[T] (Evidence at Transcript Level) = 27
PDBs = 27
Bacteria
Sequence EC Number Organism GenBank ID RefSeq UniProt PDB
Beta-hydroxyacyl-ACP dehydratase {ECO:0000255|HAMAP-Rule:MF_00406} 4.2.1.59 {ECO:0000255|HAMAP-Rule:MF_00406}
Burkholderia thailandensis (strain E264 / ATCC 700388 / DSM 13276 / CIP 106301). ABC39413.1
WP_011402240.1
YP_442562.1
Q2SWY7 [P]
Q2SWY7.1
4H4G
Beta-hydroxyacyl-ACP dehydratase {ECO:0000256|HAMAP-Rule:MF_00406} 4.2.1.59 {ECO:0000255|HAMAP-Rule:MF_00406}
4.2.1.59 {ECO:0000256|HAMAP-Rule:MF_00406}
Campylobacter jejuni subsp. jejuni CG8486. AAW34912.1
ABV51849.1
ADC27901.1
ADT72027.1
AFU42391.1
AHK51594.1
AHK53259.1
AHK54925.1
AHK56590.1
AHK58254.1
AHY39532.1
AIW09535.1
AJA54387.1
AJK72164.1
AJK82197.1
AJK84082.1
CAL34427.1
CCK66404.1
EAQ59971.1
EAQ73095.1
EAQ94305.1
EDK21495.1
EDZ32831.1
EFV06545.1
EFV09425.1
EHI15387.1
EIB17813.1
EIB26478.1
EIB28164.1
EIB35080.1
EIB37201.1
EIB43600.1
EIB48377.1
EIB52416.1
EIB57251.1
EIB57681.1
EIB63713.1
EIB64074.1
EIB68650.1
EIB71709.1
EIB87646.1
EPW33812.1
ETJ82895.1
ETJ84161.1
ETN90515.1
EXU94159.1
KDA19191.1
KDA19816.1
KDA21751.1
KDA23784.1
KDA24811.1
KDA28697.1
KDA29978.1
KGF74969.1
WP_002857452.1
YP_001481826.1
YP_002343715.1
YP_178342.1
YP_999988.1
A0A0B4QQT2
A0A0B6U0P7
A1VXZ7 [P]
A1VXZ7.1
A5KI92
A8FK62
A8FK62.1
Q5HWJ3
Q5HWJ3.1
Q9PIM2
Q9PIM2.1
W8ILV5
W8IRF6
W8J594
W8JEJ8
W8JJ65
3D6X
Beta-hydroxyacyl-ACP dehydratase {ECO:0000256|HAMAP-Rule:MF_00406} 4.2.1.59 {ECO:0000256|HAMAP-Rule:MF_00406}
Helicobacter pylori (Campylobacter pylori). AAW22049.1
EKE92770.1
WP_000438088.1
K2LS43
Q5G940 [P]
3B7J
3CF8
3CF9
3D04
3DOY
3DOZ
3DP0
3DP1
3DP2
3DP3
3ED0
Beta-hydroxyacyl-ACP dehydratase {ECO:0000255|HAMAP-Rule:MF_00406} 4.2.1.59 {ECO:0000255|HAMAP-Rule:MF_00406}
Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori). AAD08419.1
AFV42595.1
AFV44190.1
AFV45783.1
AJF09594.1
AJF11135.1
NP_208167.1
WP_000438056.1
YP_006935298.1
A0A0B5FY27
K4NTH3
O25928 [P]
O25928.1
2GLL
2GLM
2GLP
2GLV
Beta-hydroxyacyl-ACP dehydratase {ECO:0000255|HAMAP-Rule:MF_00406} 4.2.1.59 {ECO:0000255|HAMAP-Rule:MF_00406}
Neisseria meningitidis serogroup C / serotype 2a (strain ATCC 700532 / DSM 15464 / FAM18). AIZ18064.1
AIZ19643.1
AIZ21523.1
AIZ23476.1
AIZ26363.1
CAM09489.1
CBA05936.1
CBA08338.1
EGC51947.1
EGC55765.1
EGC61617.1
EJU75706.1
EJU80202.1
ELK68381.1
ELK75185.1
ELK79333.1
ELK80430.1
ELK87002.1
ELK92671.1
ELK93123.1
ELK93460.1
ELK99299.1
EOB96001.1
EOB98368.1
EOC02411.1
EOC02455.1
EOC04624.1
EOC14143.1
EOC25681.1
EOC28459.1
EOC30087.1
EOC31798.1
EOC37611.1
EOC40871.1
EOC43337.1
EOC43791.1
EOC44683.1
EOC46951.1
EOC47472.1
EOC49973.1
EOC54361.1
EOC55288.1
EPF58515.1
KGI98970.1
KHC98310.1
KHC99830.1
KHF23714.1
KID54366.1
KIF91004.1
KIF91280.1
KIF93045.1
KIF93552.1
WP_002216259.1
YP_003083998.1
YP_974299.1
A0A0C1Q1G9
A1KRL1 [P]
A1KRL1.1
C6S9B9
C6SCE8
J8VCU6
L5RYK6
4I83
Beta-hydroxyacyl-ACP dehydratase {ECO:0000256|HAMAP-Rule:MF_00406} 4.2.1.59 {ECO:0000255|HAMAP-Rule:MF_00406}
4.2.1.59 {ECO:0000256|HAMAP-Rule:MF_00406}
Pseudomonas aeruginosa (strain ATCC 29260 / PA103). AAG07033.1
ABJ12878.1
ABR82636.1
AEO73788.1
AFM63516.1
AGI80239.1
AGO41193.1
AGV62094.1
AGV63996.1
AGY63388.1
AGY70144.1
AHA17416.1
AHA23215.1
AHB54574.1
AHC64028.1
AHC75524.1
AHH52431.1
AHK82325.1
AHK88227.1
AHK94147.1
AHL00171.1
AHL06122.1
AHL12052.1
AHW69791.1
AID74834.1
AID86182.1
AJD62688.1
AJF51172.1
BAK91599.1
BAP21733.1
BAP49367.1
BAQ38194.1
CAW26118.1
CCQ88450.1
CDH69705.1
CDH75784.1
CDI92069.1
CDM44356.1
CDM50426.1
CDO83125.1
CEI05362.1
CEI78508.1
EAZ54001.1
EAZ59784.1
EFQ40118.1
EHF15543.1
EHS36410.1
EHS44152.1
EIE44986.1
EJY62654.1
EJZ74019.1
EKA35582.1
EKA46058.1
EKA48605.1
EKA56432.1
EKA58361.1
EME95062.1
EMZ55330.1
EMZ56071.1
ENH92561.1
EOQ77989.1
EOT11337.1
EOT19229.1
EOT23264.1
EQL39412.1
EQM89147.1
ERF09182.1
ERU41870.1
ERU42862.1
ERU43376.1
ERU53612.1
ERU63741.1
ERU66231.1
ERU75018.1
ERU84789.1
ERU85306.1
ERU97808.1
ERV01218.1
ERV03272.1
ERV16400.1
ERV19704.1
ERV21997.1
ERV33807.1
ERV35677.1
ERV47053.1
ERV50088.1
ERV54754.1
ERV61439.1
ERV68162.1
ERV71107.1
ERV81584.1
ERV93679.1
ERV94736.1
ERV97881.1
ERW02290.1
ERW03427.1
ERW17738.1
ERW22423.1
ERW27042.1
ERW29887.1
ERW34289.1
ERW46499.1
ERW48637.1
ERW51955.1
ERW67711.1
ERW72633.1
ERW82731.1
ERW86606.1
ERW88250.1
ERW95536.1
ERX08433.1
ERX10455.1
ERX14136.1
ERX16305.1
ERX25370.1
ERX39860.1
ERX43345.1
ERX47314.1
ERX52839.1
ERX58430.1
ERX63755.1
ERX65767.1
ERX71412.1
ERX79046.1
ERX84892.1
ERX87462.1
ERX92150.1
ERX98343.1
ERY15067.1
ERY18692.1
ERY20999.1
ERY31886.1
ERY37088.1
ERY40924.1
ERY48535.1
ERY56951.1
ERY58663.1
ERY69466.1
ERY70517.1
ERY76431.1
ERY80416.1
ERY82172.1
ERY89042.1
ERZ02560.1
ERZ05165.1
ERZ17136.1
ERZ18282.1
ERZ30168.1
ERZ32161.1
ERZ43164.1
ERZ45285.1
ESQ68000.1
ESR68714.1
ESR96107.1
ESZ81069.1
ETD43864.1
ETD56947.1
ETD73930.1
ETU78511.1
ETU80746.1
ETU89424.1
ETU98720.1
ETU99911.1
ETV02836.1
ETV11517.1
ETV18618.1
ETV29492.1
ETV32285.1
ETV44308.1
ETV45037.1
ETV51292.1
ETV57179.1
ETV61587.1
EVT84745.1
EWH29410.1
EYU02299.1
EYU07031.1
EZN47219.1
EZN54499.1
EZN58060.1
EZN67488.1
EZN73012.1
EZN79242.1
EZN82775.1
EZN93259.1
EZN94485.1
EZO02674.1
EZO06715.1
EZO14399.1
EZO19184.1
EZO25851.1
EZO33676.1
EZO36290.1
EZO46550.1
EZO55562.1
EZO56378.1
EZO63505.1
EZO70946.1
EZO78472.1
EZO85844.1
EZO87058.1
EZP00778.1
EZP03974.1
EZP07290.1
EZP19552.1
EZP21344.1
EZP24824.1
GAA15870.1
GAJ56257.1
KAJ10095.1
KAJ10416.1
KAJ27279.1
KAJ91478.1
KDR48556.1
KEA10445.1
KEA17911.1
KEA22313.1
KEA30008.1
KEA42456.1
KEF92803.1
KEI29284.1
KFB17752.1
KFF35973.1
KFL12541.1
KGB88288.1
KGD97466.1
KHE36925.1
KHE60405.1
KHE65597.1
KJC18699.1
KJC25364.1
KJJ20533.1
NP_252335.1
WP_003092375.1
YP_001346878.1
YP_002438994.1
YP_008553901.1
YP_008559402.1
YP_008695543.1
YP_008707824.1
YP_789519.1
A0A022P8I4
A0A031E6U5
A0A069QFG1
A0A086C1A9
A0A0B6WGM3
A6V1E3
A6V1E3.1
B7V7U3
B7V7U3.1
K1DUD2
N2CV84
Q02RB7
Q02RB7.1
Q9HXY7 [P]
Q9HXY7.1
S0HTK3
S0IRP2
U8MPR2
U8NPB5
U9IKX8
V6AAQ0
V8F0G2
W0WB82
W0YY27
W1MH56
X6ZAM5
X7DX10
Z2DA98
1U1Z
Eukaryota
Sequence EC Number Organism GenBank ID RefSeq UniProt PDB
Fatty acid synthesis protein {ECO:0000313|EMBL:AAM75408.1} Plasmodium falciparum. AAK83685.1
AAM75408.1
CAD52378.1
ETW34864.1
ETW41010.1
ETW47647.1
ETW54640.1
ETW59634.1
EUR66229.1
EUT81268.1
XP_001349970.1
A0A024W1R3
A0A024WKE5
A0A024X285
Q8I6T4
Q965D7 [P]
W4ICZ5
W4IXB9
W7EW36
W7FDU5
1Z6B
1ZHG
2OKH
2OKI
3AZ8
3AZ9
3AZA
3AZB