ThYme: Thioester-active Enzymes

Family HD5

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Names of enzymes and/or genes present

FabA
3-hydroxydecanoyl-ACP dehydratases

EC numbers

4.2.1.- (Unclassified hydro-lyases)
4.2.1.60 (3-hydroxydecanoyl-ACP dehydratases)

Catalytic residues
Notes
Numbers [P] (Evidence at Protein Level) = 4
[T] (Evidence at Transcript Level) = 1
PDBs = 11
Bacteria
Sequence EC Number Organism GenBank ID RefSeq UniProt PDB
Beta-ketoacyl-ACP synthase I 2.3.1.41
Escherichia coli (strain K12).

P0A953 [P]

Trans-2-decenoyl-[acyl-carrier-protein] isomerase {ECO:0000256|HAMAP-Rule:MF_00405} 4.2.1.59 {ECO:0000255|HAMAP-Rule:MF_00405}
4.2.1.59 {ECO:0000256|HAMAP-Rule:MF_00405}
5.3.3.14 {ECO:0000255|HAMAP-Rule:MF_00405}
Escherichia coli O139:H28 (strain E24377A / ETEC). AAA96496.1
AAC44389.1
AAC44399.1
AAC74040.1
AAG55440.1
ABV05410.1
ABV19295.1
ACA78272.1
ACB02154.1
ACB17463.1
ACI34912.1
ACI85546.1
ACI85547.1
ACI85548.1
ACI85549.1
ACI85550.1
ACR62058.1
ACY27485.1
AIX66578.1
AJB54505.1
AJH13070.1
BAA35712.1
BAB34461.1
CAQ97859.1
CAR12352.1
CAR18320.1
CCJ43497.1
CCK46206.1
CDK49252.1
CDK80564.1
CDL29581.1
CDP68222.1
CDP72060.1
CDU35413.1
CDU39251.1
CDY56781.1
CDZ19804.1
CEE05196.1
EDU91165.1
EFI89427.1
EFZ60554.1
EGE65375.1
EGI10501.1
EGI22312.1
EGI46731.1
EGI51268.1
EGP25749.1
EGW95918.1
EGW97513.1
EHP66228.1
EHV49834.1
EHV62185.1
EHW14202.1
EHW23471.1
EHW75315.1
EHX34450.1
EID65942.1
EIG79305.1
EIG95599.1
EIH15456.1
EIH25862.1
EII11014.1
EII22531.1
EII34681.1
EII47063.1
EII57774.1
EJE59994.1
EJE85806.1
EKJ25899.1
EKJ82783.1
ELW37917.1
EMU64203.1
EMU71211.1
EMV62980.1
EMV63536.1
EMW23196.1
EMW85738.1
EMX22249.1
EMX31905.1
EMX41546.1
EMX54021.1
EMX88935.1
ENA09245.1
ENA34971.1
ENA40817.1
ENB14825.1
ENB29881.1
ENB43813.1
ENC36622.1
ENC41774.1
ENC92700.1
END55123.1
END93987.1
ENG99243.1
ENH04071.1
ENH10285.1
EQX89546.1
ESA31744.1
ETD62369.1
EYD85389.1
EYE28593.1
EYV15163.1
EYV52794.1
EYY75236.1
EZA29323.1
EZB62855.1
EZD33477.1
EZD91749.1
EZD94449.1
EZD99238.1
EZE26127.1
EZE56203.1
EZJ88245.1
EZK24500.1
KDU20660.1
KDU23821.1
KDU32283.1
KDU55411.1
KDU62381.1
KDV35493.1
KDV38680.1
KDV59613.1
KDW33604.1
KDW77073.1
KDW84924.1
KDX20681.1
KDX90109.1
KDY23433.1
KDY53791.1
KDY62546.1
KDY66293.1
KDY87102.1
KDY96470.1
KDZ16747.1
KDZ37928.1
KDZ67934.1
KEJ50660.1
KEJ52775.1
KEJ64446.1
KEJ69904.1
KEJ78956.1
KEL27591.1
KEL66528.1
KEM54426.1
KEN50777.1
KEN72645.1
KEN91719.1
KEO00579.1
KEO03124.1
KEO13860.1
KEO26920.1
KEO36253.1
KFD76390.1
KHD42831.1
KHD47963.1
KHG96297.1
KHH05594.1
KHH08516.1
KHI34701.1
KHI88973.1
KHJ18468.1
KIG54244.1
KIG83537.1
KIH02785.1
KIH31943.1
KII09610.1
KIN84896.1
NP_286829.1
NP_309065.1
NP_415474.1
YP_001457793.1
YP_001462186.1
YP_001725599.1
YP_001729932.1
YP_001744216.1
YP_002269622.1
YP_002386454.1
YP_002408156.1
YP_002411896.1
YP_002926008.1
YP_489226.1
A0A017IH73
A0A017LYX2
A0A024KTE8
A0A025CIE3
A0A025FK05
A0A026GXK6
A0A026UI20
A0A027FAK0
A0A027U895
A0A027YZG1
A0A027Z730
A0A027ZKH4
A0A028BRW4
A0A028E8E8
A0A029LRC5
A0A029PRD4
A0A069X3V7
A0A069XQ29
A0A069ZDK3
A0A070D2W4
A0A070DE19
A0A070F2I7
A0A070KPC6
A0A070PIF3
A0A070PWW1
A0A070SSL7
A0A070YI55
A0A071AL26
A0A071BVC3
A0A071CD65
A0A071DA73
A0A071FD10
A0A073G0E8
A0A073GU96
A0A073GXJ5
A0A073HP16
A0A073TYP6
A0A073UEI8
A0A074HX14
A0A074I4B3
A0A074IMS1
A0A079A6V6
A0A079B1T5
A0A079DMV9
A0A079F7D7
A0A079FWH5
A0A079H5Z3
A0A079XYN7
A0A080CDI2
A0A080ENI2
A0A080G287
A0A080GUT1
A0A080IGZ0
A0A080J9P8
A7ZK57
A7ZYQ6
B1IVX8
B1LJQ9
B1X8Q8
B3BHT3
B5YT84
B7M883
B7N3B6
B7NM20
C3TFR2
C4ZQ80
D0VEX0
D8BV84
E7I4T2
F3LXF2
F4SMF1
F4TCI2
F4VCY0
F4VT91
F7MV19
G2ADF5
G2ASB5
H1BW53
H4TZW1
H4UGK7
H4YTY1
H4ZS26
H5DYE6
H5IGP7
I0VP76
I2RAM0
I2S5T3
I2SYJ1
I2VX81
I2WD03
I2WVA6
I2XDJ3
I2XUG2
J7QZS6
K3RPV8
K4V3E6
K4Y1V4
K5CNZ3
L9IMG6
M8KYA6
M8L6F5
M8TEG6
M8U292
M8Z0Z6
M9E1Q7
M9FPL6
M9FWW0
M9I2L5
M9J395
M9KQ54
N2H8I3
N2JGE3
N2JNI5
N2QU51
N2S635
N2T6I4
N3AQB7
N3B5P2
N3FJ99
N3KIV1
N3NXS1
N4NE22
N4P708
N4PMF9
P0A6Q3 [P]
P0A6Q4
T9AI64
U9VGD6
V6ECP3
V6FN47
V8FDK2
W1BM50
W1F5H6
1MKA
1MKB
4KEH
Trans-2-decenoyl-[acyl-carrier-protein] isomerase {ECO:0000256|HAMAP-Rule:MF_00405} 4.2.1.59
4.2.1.59 {ECO:0000255|HAMAP-Rule:MF_00405}
4.2.1.59 {ECO:0000256|HAMAP-Rule:MF_00405
ECO:0000256|SAAS:SAAS00064166}
4.2.1.59 {ECO:0000256|HAMAP-Rule:MF_00405}
5.3.3.14
5.3.3.14 {ECO:0000255|HAMAP-Rule:MF_00405}
Pseudomonas aeruginosa ATCC 25324. AAC45619.1
AAG04999.1
ABJ10791.1
ABR85460.1
AEO75920.1
AFM65811.1
AGI82348.1
AGO39412.1
AGV62724.1
AGV67198.1
AGY66000.1
AGY69600.1
AHA21097.1
AHA26896.1
AHB56772.1
AHC66366.1
AHC77912.1
AHH50362.1
AHK84595.1
AHK90496.1
AHK96474.1
AHL02439.1
AHL08360.1
AHL14314.1
AHW71921.1
AID72820.1
AJD64859.1
AJF49081.1
BAK89359.1
BAP24036.1
BAP51629.1
BAQ40758.1
CAW28444.1
CCQ85141.1
CDH70920.1
CDH78066.1
CDI89789.1
CDM46628.1
CDM52617.1
CDO80660.1
CEI19513.1
CEI77168.1
EAZ52152.1
EAZ57398.1
EFQ37945.1
EHF13273.1
EHS35016.1
EHS41216.1
EIE44632.1
EJY60402.1
EJZ76310.1
EKA32184.1
EKA38721.1
EKA42473.1
EKA48821.1
EKA53303.1
EME94681.1
EMZ47397.1
EMZ48829.1
ENH94907.1
EOT13041.1
EOT15760.1
EOT21350.1
EQM87652.1
ERF07649.1
ERU34272.1
ERU37931.1
ERU49425.1
ERU56180.1
ERU57341.1
ERU68199.1
ERU70648.1
ERU78173.1
ERU79473.1
ERU89510.1
ERU95915.1
ERV01708.1
ERV10286.1
ERV12770.1
ERV14221.1
ERV29839.1
ERV32708.1
ERV38300.1
ERV41423.1
ERV43791.1
ERV50497.1
ERV52057.1
ERV74894.1
ERV78361.1
ERV87114.1
ERV87526.1
ERV87973.1
ERW02634.1
ERW07071.1
ERW19424.1
ERW23035.1
ERW28194.1
ERW32793.1
ERW36798.1
ERW53725.1
ERW56074.1
ERW57551.1
ERW62566.1
ERW64579.1
ERW73396.1
ERW79341.1
ERW80715.1
ERW94347.1
ERX01851.1
ERX04034.1
ERX10125.1
ERX19619.1
ERX21844.1
ERX35294.1
ERX35660.1
ERX39203.1
ERX50927.1
ERX55741.1
ERX61609.1
ERX70662.1
ERX74812.1
ERX79513.1
ERX89396.1
ERX94396.1
ERY04274.1
ERY06772.1
ERY11999.1
ERY15835.1
ERY25406.1
ERY30571.1
ERY32374.1
ERY46001.1
ERY47269.1
ERY52402.1
ERY63960.1
ERY66624.1
ERY79771.1
ERY80602.1
ERY96860.1
ERY97777.1
ERY98104.1
ERZ08523.1
ERZ11702.1
ERZ21536.1
ERZ24324.1
ERZ28177.1
ERZ36892.1
ERZ39584.1
ERZ48437.1
ESQ63756.1
ESR98524.1
ESZ83574.1
ETU74809.1
ETU77841.1
ETU85229.1
ETU89651.1
ETV05344.1
ETV07755.1
ETV14961.1
ETV16403.1
ETV25792.1
ETV35530.1
ETV36091.1
ETV39575.1
ETV47401.1
ETV53612.1
ETV62837.1
EWH27018.1
EYU02407.1
EYU03878.1
EZN48256.1
EZN55497.1
EZN58237.1
EZN65957.1
EZN71122.1
EZN74304.1
EZN81062.1
EZN89322.1
EZN95588.1
EZO04572.1
EZO08839.1
EZO14062.1
EZO19505.1
EZO24637.1
EZO37629.1
EZO38148.1
EZO48566.1
EZO51240.1
EZO53367.1
EZO58155.1
EZO67208.1
EZO69822.1
EZO75863.1
EZO82687.1
EZO93264.1
EZO95288.1
EZO99653.1
EZP12998.1
EZP14891.1
EZP22566.1
GAA17158.1
GAJ55080.1
KAJ10549.1
KAJ13388.1
KAJ24875.1
KAJ28255.1
KAJ89346.1
KDR46087.1
KEA13909.1
KEA15842.1
KEA27736.1
KEF93273.1
KEI26683.1
KFL12790.1
KGB85098.1
KGD98657.1
KHE34896.1
KHE61351.1
KHE61840.1
KJC16740.1
KJC19849.1
KJJ14373.1
NP_250301.1
WP_003087475.1
YP_001349018.1
YP_002441300.1
YP_008551821.1
YP_008557487.1
YP_008693460.1
YP_008705741.1
YP_791641.1
A0A022P1E0
A0A031D1U9
A0A072ZI65
A0A0B6WJX4
A6V7I3
A6V7I3.1
B7UVB1
B7UVB1.1
K1D0R8
N2C0P2
O33877 [P]
O33877.1
Q02K95
Q02K95.1
S0IE92
S0IY74
U8MBY2
U8N5I2
U9HWP2
V6AHN1
W0WEN1
W0YRM2
X6XJ39
X7E0G4
4B0B
4B0C
4B0I
4B0J
4B8U
4CL6
4FQ9
Trans-2-decenoyl-[acyl-carrier-protein] isomerase {ECO:0000255|HAMAP-Rule:MF_00405} 4.2.1.59 {ECO:0000255|HAMAP-Rule:MF_00405}
5.3.3.14 {ECO:0000255|HAMAP-Rule:MF_00405}
Yersinia pseudotuberculosis serotype O:1b (strain IP 31758). ABP39930.1
ABS49728.1
ACA68911.1
ACC88528.1
ACY58179.1
ACY61942.1
ADE64215.1
ADV99274.1
AEL74372.1
AIN13993.1
AJI91845.1
AJI97742.1
AJJ02928.1
AJJ07993.1
AJJ16339.1
AJJ30865.1
AJJ40327.1
AJJ44393.1
AJJ50753.1
AJJ56309.1
AJJ59351.1
AJJ65470.1
AJJ70120.1
AJJ75118.1
AJJ78890.1
AJJ84882.1
AJJ89756.1
AJK08604.1
AJK12517.1
AJK17123.1
AJK21121.1
AJK24564.1
CAH20690.1
EDM41043.1
EDR40901.1
EDR41453.1
EDR52069.1
EDR58390.1
EDR62032.1
EDR66698.1
EEO81516.1
EEO87819.1
EEO90846.1
EFA46188.1
EIQ90702.1
EIQ91894.1
EIQ93112.1
EIR04777.1
EIR05853.1
EIR08975.1
EIR19781.1
EIR20797.1
EIR22655.1
EIR34620.1
EIR35817.1
EIR35932.1
EIR48429.1
EIR49465.1
EIR51692.1
EIR62780.1
EIR63298.1
EIR67186.1
EIR76768.1
EIR79101.1
EIR91121.1
EIR93237.1
EIR94276.1
EIS06895.1
EIS07336.1
EIS08456.1
EIS20286.1
EIS20726.1
EIS30310.1
EIS30938.1
EIS34039.1
EIS45648.1
EIS45655.1
EIS47211.1
EIS58400.1
EIS59124.1
EIS64429.1
EIS68698.1
EIS78521.1
EIS79816.1
EIS80607.1
EIS89080.1
EIS93903.1
EIS98336.1
EIT00550.1
EIT06483.1
EIT16776.1
EIT18137.1
EIT18670.1
EIT29340.1
EIT32542.1
EIT33767.1
EIT41307.1
EIT47978.1
EIT48428.1
EIT57859.1
EIT60614.1
EIT64081.1
EKS47111.1
ERP75279.1
ERP75903.1
ERP76390.1
ERP83350.1
GAE13704.1
KFB58710.1
KGA51940.1
KGA62826.1
KJG82681.1
KJG83156.1
WP_002220006.1
YP_001401511.1
YP_069981.1
A0A0B6GM96
A0A0B6HGE2
A0A0B6KZ80
A0A0B6LI73
A0A0B6LUU8
A0A0B6MXL4
A0A0B6MYG2
A0A0B6NN87
A0A0B6NZG1
A0A0B6PDL8
A0A0B6PJM7
A0A0B6Q0M6
A0A0B6QLT1
A4TKW8
A7FJT3
A7FJT3.1
A9R7H1.1
B1JQR0
B2JYT1
D0JJ81
D0JTA9
D5B5C1
Q1CA31.2
Q1CGK4.2
Q66CF3 [P]
Q66CF3.1
Q8ZG80.1
3Q62
Eukaryota
Sequence EC Number Organism GenBank ID RefSeq UniProt PDB
Polyketide synthase subunit C {ECO:0000313|EMBL:AIJ29324.1} Aurantiochytrium sp. L-BL10. AIJ29324.1

A0A076NDM8 [T]