ThYme: Thioester-active Enzymes

Family HD4

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Names of enzymes and/or genes present

HD domain of fatty acid synthases (FAS)
 

EC numbers

4.2.1.61 (3-hydroxypalmitoyl-ACP dehydratases)

Catalytic residues
Notes
Numbers [P] (Evidence at Protein Level) = 5
[T] (Evidence at Transcript Level) = 22
PDBs = 2
Eukaryota
Sequence EC Number Organism GenBank ID RefSeq UniProt PDB
Fatty acid synthase {ECO:0000313|EMBL:AGR49310.1} Agrotis ipsilon (Black cutworm moth). AGR49310.1

U5KGX9 [T]

Fatty acid synthase {ECO:0000313|EMBL:AID66643.1} Agrotis segetum (turnip moth). AID66643.1

A0A068FL27 [T]

Fatty acid synthase {ECO:0000313|EMBL:AEY83835.1} 2.3.1.85 {ECO:0000313|EMBL:AEY83835.1}
Bombus lucorum (White-tailed bumblebee). AEY83835.1

H6WCY9 [T]

Fatty acid synthase {ECO:0000313|EMBL:AEW43642.1} 2.3.1.85 {ECO:0000313|EMBL:AEW43642.1}
Bombus terrestris (Buff-tailed bumblebee) (Apis terrestris). AEW43642.1
NP_001267840.1
G9JWG5 [T]

P270 {ECO:0000313|EMBL:AAB53258.1} Bombyx mori (Silk moth). AAB53258.1
NP_001037478.1
O01678 [T]

P260 {ECO:0000313|EMBL:AAB53257.1} Bombyx mori (Silk moth). AAB53257.1
NP_001037476.1
O01677 [T]

Oleoyl-[acyl-carrier-protein] hydrolase 1.1.1.100
1.3.1.39
2.3.1.38
2.3.1.39
2.3.1.41
2.3.1.85
3.1.2.14
4.2.1.59
Bos taurus (Bovine). AAR17600.1
AAR19788.1
NP_001012687.1
Q71SP7 [T]
Q71SP7.1

Fatty acid synthase {ECO:0000313|EMBL:ABB36643.1} Capra hircus (Goat). ABB36643.1

Q076H7 [T]

Fatty acid synthase {ECO:0000313|EMBL:ABI95140.2} Capra hircus (Goat). ABI95140.2
NP_001272558.1
Q06B57 [T]

Fatty acid synthase {ECO:0000313|EMBL:JAB92698.1} Ceratitis capitata (Mediterranean fruit fly) (Tephritis capitata).
XP_004524715.1
XP_004524716.1
W8B6N0 [T]

GH17750p {ECO:0000313|EMBL:ACJ13230.1} Drosophila melanogaster (Fruit fly). ACJ13230.1

B6IDT3 [T]

V(2)k05816, isoform A {ECO:0000313|EMBL:AAF51149.1} 1.-.-.- {ECO:0000313|EMBL:AAF51149.1}
2.3.1.38 {ECO:0000313|EMBL:AAF51149.1}
2.3.1.39 {ECO:0000313|EMBL:AAF51149.1}
2.3.1.41 {ECO:0000313|EMBL:AAF51149.1}
3.1.-.- {ECO:0000313|EMBL:AAF51149.1}
Drosophila melanogaster (Fruit fly). AAF51149.1
ACZ67868.1
NP_647613.1
Q9VQL6 [T]

GH02912p {ECO:0000313|EMBL:AAM52599.1} Drosophila melanogaster (Fruit fly). AAM52599.1

Q8MR70 [T]

MIP15305p {ECO:0000313|EMBL:ADB57067.1} Drosophila melanogaster (Fruit fly). ADB57067.1

D2NUK3 [T]

FI15913p1 {ECO:0000313|EMBL:AET14856.1} Drosophila melanogaster (Fruit fly). AET14856.1

G7H848 [T]

Oleoyl-[acyl-carrier-protein] hydrolase 1.1.1.100
1.3.1.39
2.3.1.38
2.3.1.39
2.3.1.41
2.3.1.85
3.1.2.14
4.2.1.59
Gallus gallus (Chicken). AAA48767.1
AAA82106.1
AAB46389.1

P12276 [P]
P12276.5

Oleoyl-[acyl-carrier-protein] hydrolase 1.1.1.100
1.3.1.39
2.3.1.38
2.3.1.39
2.3.1.41
2.3.1.85
3.1.2.14
4.2.1.59
Homo sapiens (Human). AAA73576.1
AAB35516.1
AAC50259.1
AAH07267.1
AAH07909.1
AAH14634.2
AAH63242.1
AAS09886.1
BAE06070.1
BAG10519.1
NP_004095.4
XP_011521840.1
P49327 [P]
P49327.3

Predicted protein {ECO:0000313|EMBL:BAK02651.1} Hordeum vulgare var. distichum (Domesticated barley). BAK02651.1

F2E5M9 [T]

Predicted protein {ECO:0000313|EMBL:BAJ93568.1} Hordeum vulgare var. distichum (Domesticated barley). BAJ93568.1

F2DEP7 [T]

Predicted protein {ECO:0000313|EMBL:BAK02053.1} Hordeum vulgare var. distichum (Domesticated barley). BAK02053.1

F2E3Y1 [T]

Fatty acid synthase {ECO:0000313|EMBL:ADM88556.1} Litopenaeus vannamei (Whiteleg shrimp) (Penaeus vannamei). ADM88556.1

F8RHR0 [T]

Oleoyl-[acyl-carrier-protein] hydrolase 1.1.1.100
1.3.1.39
2.3.1.38
2.3.1.39
2.3.1.41
2.3.1.85
3.1.2.14
4.2.1.59
Mus musculus (Mouse). AAG02285.1
AAH46513.1
AAH59850.1
BAC37895.1
CAA31525.1
CAM27545.1
NP_032014.3
P19096 [P]
P19096.2

Fatty acid synthase {ECO:0000313|EMBL:ADN04900.1} Ovis aries (Sheep). ADN04900.1

E9K9T6 [T]

Oleoyl-[acyl-carrier-protein] hydrolase 1.1.1.100
1.3.1.39
2.3.1.38
2.3.1.39
2.3.1.41
2.3.1.85
3.1.2.14
4.2.1.59
Rattus norvegicus (Rat). AAA41144.1
AAA41145.1
AAA57219.1
CAA31780.1
CAA31882.1
CAA44679.1
CAA44680.1
EDM06909.1
NP_059028.1
P12785 [P]
P12785.3

Fatty acid synthase {ECO:0000313|EMBL:AAX51683.1} Sus scrofa (Pig). AAX51683.1

Q58GK8 [T]

Fatty acid synthase {ECO:0000313|EMBL:ABR09275.1} Sus scrofa (Pig). ABR09275.1
NP_001093400.1
A5YV76 [P]
2VZ8
2VZ9
Fatty acid synthase {ECO:0000313|EMBL:AAX55638.1} Sus scrofa (Pig). AAX55638.1

Q58G70 [T]