ThYme: Thioester-active Enzymes

Family KR2

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Fold 6-phosphoglucanate dehydrogenase-like (C-terminal)
Names of enzymes and/or genes present

3-hydroxyacyl-CoA dehydrogenase
FadB, FadJ
 

EC numbers

1.1.1.- (Unclassified reductases)
1.1.1.35 (3-hydroxyacyl-CoA dehydrogenase)
1.1.1.157 (3-hydroxybutyryl-CoA dehydrogenase)
1.1.1.211 (Long-chain 3-hydroxyacyl-CoA dehydrogenase)

Catalytic residues
Notes

Some sequences involved with fatty acid oxidation

Numbers [P] (Evidence at Protein Level) = 25
[T] (Evidence at Transcript Level) = 64
PDBs = 27
Bacteria
Sequence EC Number Organism GenBank ID RefSeq UniProt PDB
3-hydroxyacyl-CoA dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01621} 1.1.1.35 {ECO:0000255|HAMAP-Rule:MF_01621}
2.3.1.16 {ECO:0000255|HAMAP-Rule:MF_01620}
4.2.1.17 {ECO:0000255|HAMAP-Rule:MF_01621}
5.1.2.3 {ECO:0000255|HAMAP-Rule:MF_01621}
5.3.3.8 {ECO:0000255|HAMAP-Rule:MF_01621}
Pseudomonas fragi. BAA01227.1
WP_016780046.1
P28790 [P]
P28793 [P]
P28793.1
1WDK
1WDL
1WDM
2D3T
Eukaryota
Sequence EC Number Organism GenBank ID RefSeq UniProt PDB
3-hydroxyacyl-CoA dehydrogenase 1.1.1.35
4.2.1.17
5.1.2.3
5.3.3.8
Arabidopsis thaliana (Mouse-ear cress). AAD18042.1
AAF26990.1
AAL32699.1
AEE74468.1
NP_187342.1
Q9ZPI5 [P]
Q9ZPI5.1
2WTB
Probable 3-hydroxyacyl-CoA dehydrogenase F54C8.1 1.1.1.35
Caenorhabditis elegans. CAA80153.1
NP_499075.1
P34439 [P]
P34439.1
4J0E
4J0F
Short-chain 3-hydroxyacyl-CoA dehydrogenase 1.1.1.35
Homo sapiens (Human). AAB54008.1
AAB54009.1
AAB58153.1
AAD13581.1
AAH00306.1
AAY41050.1
CAA65528.1
NP_001171634.2
NP_005318.3
Q16836 [P]
Q16836.3
1F0Y
1F12
1F14
1F17
1IL0
1LSJ
1LSO
1M75
1M76
2HDH
3HAD
3RQS
3-hydroxyacyl-CoA dehydrogenase 1.1.1.35
4.2.1.17
5.3.3.8
Rattus norvegicus (Rat). AAA41825.1
AAA41826.1
AAH89777.1
EDL78038.1
NP_598290.1
P07896 [P]
P07896.2
1ZCJ
2X58
3ZW8
3ZW9
3ZWA
3ZWB
3ZWC
Short-chain 3-hydroxyacyl-CoA dehydrogenase 1.1.1.35
Sus scrofa (Pig). AAD20939.1
NP_999496.1
P00348 [P]
P00348.2
3HDH