ThYme: Thioester-active Enzymes

Family TE1

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Names of enzymes and/or genes present Acetyl-CoA hydrolase 1 (Ach1)
EC numbers 3.1.2.1 (acetyl-CoA hydrolase)
2.8.3.- (CoA transferases)
Catalytic residues -
Notes

1. Involved with acetate levels and CoA transfer in mitochondria
2. Act primarily on Acetyl-CoA.

 

Numbers [P] (Evidence at Protein Level) = 4
[T] (Evidence at Transcript Level) = 3
PDBs = 14
Bacteria
Sequence EC Number Organism GenBank ID RefSeq UniProt PDB
Succinyl-coenzyme A (CoA):acetate CoA-transferase {ECO:0000303|PubMed:18502856, ECO:0000303|PubMed:23030530} 2.8.3.18 {ECO:0000269|PubMed:18502856
ECO:0000269|PubMed:23030530
ECO:0000269|Ref.3}
Acetobacter aceti. ACD85596.1
AGG68319.1
AGG68324.1
BAA02549.1
KDE21007.1
WP_042786640.1
A0A063X8M7
B3EY95 [P]
B3EY95.1
4EU3
4EU4
4EU5
4EU6
4EU7
4EU8
4EU9
4EUA
4EUB
4EUC
4EUD
4FAC
Succinyl-CoA:coenzyme A transferase 2.8.3.-
Clostridium kluyveri (strain ATCC 8527 / DSM 555 / NCIMB 10680). AAA92346.1
BAH07715.1
EDK35024.1
WP_012103359.1
YP_001396395.1
B9E5E0
P38946 [T]
P38946.1

Propionyl-CoA:succinate-CoA transferase {ECO:0000313|EMBL:EGI09307.1} 2.8.3.-
2.8.3.- {ECO:0000313|EMBL:CDP73986.1}
2.8.3.- {ECO:0000313|EMBL:CDY61362.1}
2.8.3.- {ECO:0000313|EMBL:EFK92736.1}
2.8.3.- {ECO:0000313|EMBL:EII46065.1}
2.8.3.- {ECO:0000313|EMBL:EYE22232.1}
2.8.3.- {ECO:0000313|EMBL:KDU63317.1}
2.8.3.- {ECO:0000313|EMBL:KDX21102.1}
2.8.3.- {ECO:0000313|EMBL:KDX87701.1}
2.8.3.- {ECO:0000313|EMBL:KDY18685.1}
2.8.3.- {ECO:0000313|EMBL:KDY51551.1}
2.8.3.- {ECO:0000313|EMBL:KDY57383.1}
2.8.3.- {ECO:0000313|EMBL:KDY58961.1}
2.8.3.- {ECO:0000313|EMBL:KDY89432.1}
2.8.3.- {ECO:0000313|EMBL:KDY96774.1}
2.8.3.- {ECO:0000313|EMBL:KDZ18372.1}
2.8.3.- {ECO:0000313|EMBL:KDZ40767.1}
2.8.3.- {ECO:0000313|EMBL:KEJ48636.1}
2.8.3.- {ECO:0000313|EMBL:KEJ66736.1}
2.8.3.- {ECO:0000313|EMBL:KEN88570.1}
2.8.3.- {ECO:0000313|EMBL:KEN95942.1}
2.8.3.- {ECO:0000313|EMBL:KEO08144.1}
2.8.3.- {ECO:0000313|EMBL:KEO22577.1}
2.8.3.- {ECO:0000313|EMBL:KGM66101.1}
Escherichia coli H736. AAA69087.1
AAC75957.1
ACR65283.1
ACT27886.1
ACT40403.1
ACT44568.1
AEE58152.1
AEJ58252.1
AFG41846.1
AHM29998.1
AHM33252.1
AHM37859.1
AIF38236.1
AIN33282.1
AIZ29395.1
AIZ52720.1
AIZ90049.1
AJB52981.1
AJF57725.1
AJF78023.1
AJH11540.1
BAE76984.1
BAL39607.1
CAQ33231.1
CBG35954.1
CBJ02614.1
CCP99358.1
CCQ01400.1
CDJ73922.1
CDK81156.1
CDP73986.1
CDU41177.1
CDY61362.1
CDZ21712.1
EFJ68604.1
EFK16381.1
EFK92736.1
EGB32369.1
EGB56405.1
EGB66959.1
EGI09307.1
EGU26850.1
EGV47718.1
EGW66101.1
EGX04623.1
EGX16651.1
EHN83722.1
EHV55162.1
EHV58329.1
EIF16986.1
EIF85415.1
EII46065.1
EII74230.1
EIJ02683.1
EIL67306.1
EKI25986.1
EKJ83252.1
ELD28078.1
ELE62314.1
ELE69768.1
ELF06975.1
ELF18043.1
ELF35899.1
ELF71373.1
ELH01198.1
ELH46303.1
ELJ55576.1
EMD05781.1
EMD07435.1
EMR93813.1
EMS07009.1
EMW33743.1
EMX29459.1
ENA12955.1
ENA19232.1
ENA95966.1
ENB38865.1
ENB60411.1
ENB62470.1
ENB75058.1
ENB76828.1
ENB77208.1
ENB86566.1
ENC02335.1
END41077.1
END65364.1
ENG83735.1
EOU57234.1
EOV10080.1
EOV73278.1
EOV76734.1
EOW19925.1
EOW58008.1
EOW93802.1
EQP33669.1
EQQ18886.1
EQS92496.1
EQU73086.1
EQV06361.1
EQV52035.1
EQV98816.1
EQX82115.1
EQY57322.1
EQY86071.1
EQY96369.1
EQY99194.1
EQZ34193.1
EQZ37963.1
ERA16114.1
ERA98805.1
ERB18563.1
ERB21721.1
ESA65060.1
ESA92846.1
ESE05064.1
ESL33819.1
ESP36468.1
ESP43221.1
EST62966.1
EST79428.1
ETY41667.1
EYB43171.1
EYB64396.1
EYD82433.1
EYE11464.1
EYE19155.1
EYE20848.1
EYE22232.1
EYE33644.1
EZA71865.1
EZJ35363.1
EZJ52688.1
EZJ69387.1
EZK06706.1
EZK17709.1
KDA78487.1
KDA83686.1
KDP14423.1
KDS97518.1
KDS98588.1
KDT04631.1
KDT17327.1
KDT17943.1
KDT30783.1
KDT36924.1
KDT49336.1
KDT70075.1
KDT74579.1
KDT89093.1
KDT90081.1
KDT96797.1
KDU11648.1
KDU39831.1
KDU51362.1
KDU63317.1
KDU67497.1
KDV81581.1
KDW00537.1
KDW06964.1
KDW49292.1
KDW78642.1
KDW96525.1
KDX21102.1
KDX39716.1
KDX45689.1
KDX55866.1
KDX62061.1
KDX71202.1
KDX87701.1
KDY18685.1
KDY46098.1
KDY51551.1
KDY57383.1
KDY58961.1
KDY70873.1
KDY77608.1
KDY80415.1
KDY89432.1
KDY96774.1
KDZ04493.1
KDZ18372.1
KDZ40767.1
KDZ69161.1
KDZ69284.1
KDZ85458.1
KDZ85577.1
KEJ48636.1
KEJ66736.1
KEK97293.1
KEL00703.1
KEL03439.1
KEL10409.1
KEL14725.1
KEL18054.1
KEL24994.1
KEL38051.1
KEL54413.1
KEL60177.1
KEM05153.1
KEM06361.1
KEM31607.1
KEM61003.1
KEM71497.1
KEM88589.1
KEM90533.1
KEN02262.1
KEN23202.1
KEN23336.1
KEN40603.1
KEN53262.1
KEN62061.1
KEN75706.1
KEN88570.1
KEN95942.1
KEO07915.1
KEO08144.1
KEO22577.1
KEP09377.1
KEP19655.1
KGL71511.1
KGM66101.1
KGM71431.1
KGM75143.1
KGM85029.1
KHD42217.1
KHD47741.1
KHD50895.1
KHD55612.1
KHH55508.1
KHH64701.1
KHH67260.1
KHH95704.1
KHI14501.1
KHI24238.1
KHI62543.1
KIG46389.1
KIG55234.1
KIG72686.1
KIH00744.1
KIH10463.1
KJD88045.1
NP_417395.1
WP_000449965.1
YP_491120.1
A0A017LFH9
A0A070SSY9
A0A070UW09
A0A070Y969
A0A071AU27
A0A071BYZ3
A0A071CHF4
A0A071DHZ9
A0A073GPH0
A0A074HMD5
A0A074IGD5
A0A079B1I0
A0A079D6Z8
A0A079F6K1
A0A079FIW9
A0A079H2N5
A0A079XS53
A0A080GKR7
A0A080I1V3
C5A0J0
C6EII9
C6UDE9
D3GTT2
D8AKD6
D8AX79
E1HHA4
E3PIJ5
E9YF48
F4SPJ1
G0F288
H4UNJ5
H9UWF3
I2XAP5
I4J856
K5BN32
L3UEK5
L8C703
M9GA15
N2HJL0
N2SSG1
P52043 [P]
P52043.1
S0V675
S0ZIN8
S1EE06
S1EPD5
S1HWR4
T9G0N9
T9MAC3
T9ML03
U9Y6J2
V0A530
V1B7D7
W1BKK4
W8SWR6
X7P1R5

Eukaryota
Sequence EC Number Organism GenBank ID RefSeq UniProt PDB
Acetyl-CoA deacylase 3.1.2.1
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast). EAK95537.1
EAK95674.1
XP_714589.1
XP_714720.1
P83773 [P]
P83773.2

Acyl-CoA carboxylate CoA-transferase {ECO:0000313|EMBL:CAP49328.1} Emericella nidulans (Aspergillus nidulans). CAP49328.1
EAA64254.1
XP_659151.1
A9JPD8 [T]
Q5BD33

Acetyl-CoA deacylase 3.1.2.1
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). AAA34388.1
AHY74472.1
AJP37074.1
AJP81976.1
AJP82356.1
AJP82744.1
AJP83137.1
AJP83522.1
AJP83909.1
AJP84672.1
AJP85055.1
AJP85429.1
AJP85812.1
AJP86188.1
AJP86570.1
AJP86954.1
AJP87340.1
AJP87728.1
AJP88459.1
AJP88848.1
AJP89237.1
AJP89620.1
AJP90317.1
AJP90702.1
AJP91085.1
AJP91473.1
AJP91860.1
AJP92250.1
AJP92638.1
AJP93027.1
AJP93417.1
AJP93806.1
AJP94196.1
AJP94587.1
AJP94976.1
AJP95361.1
AJP95750.1
AJP96137.1
AJP97287.1
AJP97673.1
AJP98061.1
AJP98447.1
AJP98832.1
AJP99220.1
AJP99610.1
AJP99994.1
AJQ00378.1
AJQ00767.1
AJQ01535.1
AJQ01921.1
AJQ02699.1
AJQ03086.1
AJQ03457.1
AJQ03841.1
AJQ04189.1
AJQ04575.1
AJQ06113.1
AJQ06501.1
AJQ06865.1
AJQ07248.1
AJQ07635.1
AJQ08021.1
AJQ08792.1
AJQ09178.1
AJQ09562.1
AJQ09950.1
AJQ10337.1
AJQ10723.1
AJQ11072.1
AJQ11458.1
AJQ11844.1
AJQ12606.1
AJQ12993.1
AJQ13378.1
AJQ13765.1
AJQ14149.1
AJQ14534.1
AJQ14919.1
AJQ15296.1
AJQ15674.1
AJQ16433.1
CAA48570.1
CAA84834.1
DAA07105.1
EDN64602.1
EDV12106.1
EEU04583.1
EGA59795.1
EGA76131.1
EGA80023.1
EGA88074.1
EIW12294.1
EWG87577.1
EWG92366.1
EWG97589.1
EWH19408.1
GAA21537.1
NP_009538.1
A0A023Z8F0
A0A024XVQ5
A0A024Y860
A6ZKT3
B3LNF3
C7GX95
E7K9D4
E7LR31
E7Q0T8
E7QBB3
G2W8Z4
N1P7F3
P32316 [P]
P32316.2
W7PKU7
W7RHM9

Acetyl-CoA deacylase 3.1.2.1
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). BAA13883.1
CAB52573.1
NP_594811.1
Q9UUJ9 [T]
Q9UUJ9.1