ThYme: Thioester-active Enzymes

Family TE20

Now Showing: Only Sequences with PDB Entries

Show All Sequences
Show Only Sequences with Uniprot Entries with Evidence at Protein or Transcript Level

Fold α/-Hydrolase
Names of enzymes and/or genes present Palmitoyl-protein thioesterase (ppt1, ppt2)
EC numbers 3.1.2.- (thioester hydrolase)
3.1.2.22 (palmitoyl-protein hydrolase)
Catalytic residues Ser, His, Asp
Notes

1. Palmitoyl-protein activity.
2. Mutations in PPT gene have been linked to neuronal ceroid lipofuscinosis, a genetic neurogenerative disorder.


 

Numbers [P] (Evidence at Protein Level) = 6
[T] (Evidence at Transcript Level) = 67
PDBs = 5
Eukaryota
Sequence EC Number Organism GenBank ID RefSeq UniProt PDB
Palmitoyl-protein hydrolase 1 3.1.2.22
Bos taurus (Bovine). AAA59357.1
AAI34480.1
NP_776579.1
P45478 [P]
P45478.1
1EH5
1EI9
1EXW
HCG1999928, isoform CRA_a {ECO:0000313|EMBL:EAX03592.1} 3.1.2.-
Homo sapiens (Human). AAB47495.1
AAB80730.1
AAB80731.1
AAH01355.1
ACE86903.1
ACE87590.1
BAF85418.1
CAB46981.1
CAB53659.1
CAG38577.1
CAI17424.1
CAI17426.2
CAI18342.1
CAI18344.1
CAI41763.1
CAI41797.1
CAI41798.1
CAI41799.1
CAM24823.1
CAM24825.1
CAM25714.1
CAM26213.1
CAM26215.1
CAM26216.1
CAM26218.1
CAQ06588.1
CAQ06590.1
CAQ09561.1
CAQ09617.1
CAQ09619.1
CAQ10692.1
CAQ10694.1
EAX03591.1
EAX03592.1
EAX03593.1
EAX03594.1
EAX03595.1
EAX03596.1
EAX03597.1
NP_001191032.1
NP_005146.4
A0A024RCQ8
Q9UMR5 [P]
Q9UMR5-1
Q9UMR5.4
1PJA
Palmitoyl-protein hydrolase 1 3.1.2.22
Homo sapiens (Human). AAA85337.1
AAB06236.1
AAB72224.1
AAH08426.1
ADQ31900.1
AIC49464.1
BAG35214.1
BAG63586.1
CAG46850.1
CAI11025.1
EAX07237.1
EAX07238.1
NP_000301.1
NP_001136076.1
P50897 [P]
P50897-1
P50897-2
P50897.1
3GRO