ThYme: Thioester-active Enzymes

Family HD8

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Names of enzymes and/or genes present

Hydroxyacyl-CoA dehydratase

EC numbers
Catalytic residues
Notes
Numbers [P] (Evidence at Protein Level) = 7
[T] (Evidence at Transcript Level) = 63
PDBs = 0
Eukaryota
Sequence EC Number Organism GenBank ID RefSeq UniProt PDB
Uncharacterized protein {ECO:0000313|EnsemblMetazoa:ACYPI000022-PA} Acyrthosiphon pisum (Pea aphid). ABD76375.1
NP_001119622.1
Q1ZZP8 [T]

At5g59770 {ECO:0000313|EMBL:AAO63307.1} Arabidopsis thaliana (Mouse-ear cress). AAO63307.1
BAC43694.1

Q8GW27 [T]

Protein tyrosine phosphatase-like protein 4.2.1.134 {ECO:0000305|PubMed:18799749}
Arabidopsis thaliana (Mouse-ear cress). AAL05403.1
AAL38266.1
AAP13377.1
AED91548.1
AED91549.1
CAB89395.1
CAD45041.1
NP_001078566.1
NP_196610.2
Q8VZB2 [P]
Q8VZB2-1
Q8VZB2-2
Q8VZB2.1

Protein tyrosine phosphatase {ECO:0000313|EMBL:ABF51324.1} Bombyx mori (Silk moth). ABF51324.1
NP_001040403.1
Q1HQ17 [T]

Protein-tyrosine phosphatase-like member B {ECO:0000305} 4.2.1.134 {ECO:0000250|UniProtKB:Q6Y1H2}
Bos taurus (Bovine). AAI12558.2
NP_001124229.1
Q2KIP8 [T]
Q2KIP8.2

Protein-tyrosine phosphatase-like A domain-containing protein 1 {ECO:0000305} 4.2.1.134 {ECO:0000250|UniProtKB:Q9P035}
Bos taurus (Bovine). AAI51340.1
NP_001096786.1
A7YY55 [T]
A7YY55.1

Protein-tyrosine phosphatase-like A domain-containing protein 2 {ECO:0000305} 4.2.1.134 {ECO:0000250|UniProtKB:Q9P035}
Bos taurus (Bovine). AAI20232.1
NP_001069990.1
Q0P5C7 [T]
Q0P5C7.1

PASTICCINO 2 {ECO:0000313|EMBL:ACC78512.1} Brassica rapa subsp. pekinensis (Chinese cabbage) (Brassica pekinensis). ACC78512.1

B2MWR3 [T]

3-hydroxyacyl-CoA dehydratase 2 {ECO:0000313|EMBL:JAB41904.1} Callithrix jacchus (White-tufted-ear marmoset).
XP_008980573.1
U3EI14 [T]

Uncharacterized protein {ECO:0000313|Ensembl:ENSCJAP00000016253} Callithrix jacchus (White-tufted-ear marmoset).
XP_002743015.1
F6WUZ8 [T]

3-hydroxyacyl-CoA dehydratase {ECO:0000313|EMBL:AIL29211.1} Camellia oleifera. AIL29211.1

A0A077D9L0 [T]

Protein-tyrosine phosphatase-like member A {ECO:0000305} 4.2.1.134 {ECO:0000250|UniProtKB:B0YJ81}
Canis familiaris (Dog) (Canis lupus familiaris). CAI46275.1
CAI46276.1
NP_001020440.1
Q4W1W1 [T]
Q4W1W1-1
Q4W1W1.1

Protein-tyrosine phosphatase-like A domain-containing protein 1 {ECO:0000305} 4.2.1.134 {ECO:0000250|UniProtKB:Q9P035}
Danio rerio (Zebrafish) (Brachydanio rerio). AAH55174.1
AAI62443.1
AAI62805.1
CAK03707.1
NP_001038449.1
B3DGL9
Q7SY06 [T]
Q7SY06.2

RE57556p {ECO:0000313|EMBL:AAL49155.1} Drosophila melanogaster (Fruit fly). AAL49155.1

Q8SYI0 [T]

FI03286p {ECO:0000313|EMBL:ACI16533.1} Drosophila melanogaster (Fruit fly). AAF53307.1
ACI16533.1
NP_609655.2
Q9VJX8 [T]

GH07085p {ECO:0000313|EMBL:AAL39203.1} Drosophila melanogaster (Fruit fly). AAF53144.1
AAL39203.1
NP_609534.1
Q9VKD2 [T]

Protein tyrosine phosphatase-like A domain protein containing 1 {ECO:0000313|EMBL:ACR08643.1} Drosophila silvestris (Fruit fly). ACR08643.1

C5IFR5 [T]

Similar to Drosophila melanogaster CG6746 {ECO:0000313|EMBL:AAR10157.1} Drosophila yakuba (Fruit fly). AAR10157.1

Q6XHP9 [T]

Protein-tyrosine phosphatase-like A domain-containing protein 1 {ECO:0000305} 4.2.1.134 {ECO:0000250|UniProtKB:Q9P035}
Gallus gallus (Chicken). CAG31186.1
NP_001007829.1
Q5ZM57 [T]
Q5ZM57.1

Uncharacterized protein {ECO:0000313|EnsemblPlants:GLYMA08G38280.1} Glycine max (Soybean) (Glycine hispida). ACU16199.1
NP_001235625.1
C6T3G1 [T]

Uncharacterized protein {ECO:0000313|EnsemblPlants:GLYMA11G15190.1} Glycine max (Soybean) (Glycine hispida). ACU16724.1
NP_001238624.1
C6T4V3 [T]

3-hydroxyacyl-CoA dehydratase PASTICCINO 2 {ECO:0000313|EMBL:AHA62438.1} Gossypium hirsutum (Upland cotton) (Gossypium mexicanum). AHA62438.1

V5M181 [T]

3-hydroxyacyl-CoA dehydratase PASTICCINO 2 {ECO:0000313|EMBL:AHA62439.1} Gossypium hirsutum (Upland cotton) (Gossypium mexicanum). AHA62439.1

V5M156 [T]

Protein-tyrosine phosphatase-like A domain-containing protein 1 {ECO:0000312|HGNC:HGNC:24175} 4.2.1.134 {ECO:0000269|PubMed:18554506}
Homo sapiens (Human). AAF29085.1
AAH19873.1
AAH35508.1
AAH47685.1
AAH58912.1
ABB83547.1
BAB55101.1
BAC11249.1
BAC11277.1
BAG61266.1
CAB69070.1
NP_057479.2
Q9P035 [P]
Q9P035-1
Q9P035.2

Protein-tyrosine phosphatase-like member B {ECO:0000312|HGNC:HGNC:9640} 4.2.1.134 {ECO:0000269|PubMed:18554506}
Homo sapiens (Human). AAH49369.1
AAH60839.1
AAP20101.1
AIC53384.1
BAF82672.1
NP_940684.1
Q6Y1H2 [P]
Q6Y1H2.1

Protein-tyrosine phosphatase-like member A {ECO:0000312|HGNC:HGNC:9639} 4.2.1.134 {ECO:0000269|PubMed:18554506
ECO:0000269|PubMed:23933735}
Homo sapiens (Human). AAF21976.1
AAG10713.1
AAH10353.1
AAR22554.1
ACA06059.1
ACA06060.1
ACA06061.1
NP_055056.3
B0YJ81 [P]
B0YJ81-1
B0YJ81.1

Protein-tyrosine phosphatase-like A domain-containing protein 2 {ECO:0000312|HGNC:HGNC:20920} 4.2.1.134 {ECO:0000269|PubMed:18554506}
Homo sapiens (Human). AAI14216.1
AIC53830.1
CAD97990.1
CAH70162.1
EAW58626.1
NP_001010915.2
Q5VWC8 [P]
Q5VWC8.1

Predicted protein {ECO:0000313|EMBL:BAJ99429.1} Hordeum vulgare var. distichum (Domesticated barley). BAJ99429.1

F2DWF8 [T]

Predicted protein {ECO:0000313|EMBL:BAJ96023.1} Hordeum vulgare var. distichum (Domesticated barley). BAJ96023.1

F2DLQ2 [T]

Predicted protein {ECO:0000313|EMBL:BAJ94583.1} Hordeum vulgare var. distichum (Domesticated barley). BAJ94583.1

F2DHL2 [T]

Uncharacterized protein {ECO:0000313|EnsemblPlants:MLOC_62418.3} Hordeum vulgare var. distichum (Domesticated barley). BAJ87554.1

F2CXI3 [T]

Predicted protein {ECO:0000313|EMBL:BAJ85065.1} Hordeum vulgare var. distichum (Domesticated barley). BAJ85065.1

F2CQE4 [T]

Protein tyrosine phosphatase {ECO:0000313|EMBL:AAT08740.1} Hyacinthus orientalis (Common hyacinth). AAT08740.1

Q676Y4 [T]

PHS1 {ECO:0000313|EMBL:ACO12451.1} Lepeophtheirus salmonis (Salmon louse). ACO12451.1

C1BTU8 [T]

Uncharacterized protein {ECO:0000313|EMBL:AFK47347.1} Lotus japonicus (Lotus corniculatus var. japonicus). AFK47347.1

I3T4A5 [T]

Uncharacterized protein {ECO:0000313|EMBL:AFK35984.1} Lotus japonicus (Lotus corniculatus var. japonicus). AFK35984.1

I3S6U2 [T]

Macaca fascicularis brain cDNA clone: QmoA-11863, similar to human butyrate-induced transcript 1 (HSPC121), mRNA, RefSeq: NM_016395.1 {ECO:0000313|EMBL:BAE87698.1} Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey). BAE87698.1
NP_001271561.1
I7GJV7 [T]

Uncharacterized protein {ECO:0000313|Ensembl:ENSMMUP00000033478} Macaca mulatta (Rhesus macaque). EHH27409.1
NP_001253475.1
F7GNG2 [T]

Uncharacterized protein {ECO:0000313|Ensembl:ENSMMUP00000002982} Macaca mulatta (Rhesus macaque).
NP_001248058.1
F6W0A4 [T]

Uncharacterized protein {ECO:0000313|Ensembl:ENSMMUP00000025066} Macaca mulatta (Rhesus macaque). EHH24078.1
NP_001181068.1
F6QLA6 [T]

Uncharacterized protein {ECO:0000313|EMBL:AFK41133.1} Medicago truncatula (Barrel medic) (Medicago tribuloides). AES88694.2
AFK41133.1

G7JRH2 [T]

Protein-tyrosine phosphatase-like member B {ECO:0000312|MGI:MGI:1918007} 4.2.1.134 {ECO:0000250|UniProtKB:Q6Y1H2}
Mus musculus (Mouse). AAF29489.1
AAH27289.1
AAI31900.1
AAI31902.1
BAB31092.1
BAE28371.1
EDK97870.1
NP_076076.2
Q9D3B1 [T]
Q9D3B1.1

Protein-tyrosine phosphatase-like member A {ECO:0000312|MGI:MGI:1353592} 4.2.1.134 {ECO:0000250|UniProtKB:B0YJ81}
Mus musculus (Mouse). AAF21975.1
AAI38117.1
AAI41018.1
BAB26713.1
CAM21321.1
EDL08058.1
NP_038963.3
B9EHK9
Q9QY80 [T]
Q9QY80.1

Protein-tyrosine phosphatase-like A domain-containing protein 1 {ECO:0000312|MGI:MGI:1889341} 4.2.1.134 {ECO:0000250|UniProtKB:Q9P035}
Mus musculus (Mouse). AAH31755.1
AAH57023.1
BAC34744.1
BAC35179.1
BAE20677.1
BAE35128.1
CAB10097.2
EDL26075.1
NP_067320.2
Q8K2C9 [P]
Q8K2C9.2

Protein-tyrosine phosphatase-like A domain-containing protein 2 {ECO:0000305} 4.2.1.134 {ECO:0000250|UniProtKB:Q9P035}
Mus musculus (Mouse). AAH20155.1
BAB30529.1
BAB30656.1
BAC30324.1
BAC30396.1
BAC33294.1
BAC34463.1
CAM17296.1
CAM17297.1
EDL30978.1
NP_080036.1
XP_006538252.1
XP_006538253.1
XP_006538254.1
A2AKM2 [T]
A2AKM2-1
A2AKM2.2

Protein tyrosine phosphatase-like protein 4.2.1.134 {ECO:0000250|UniProtKB:Q8VZB2}
Oryza sativa subsp. japonica (Rice). BAF14258.1
BAG87283.1
CAD39891.2
CAE01738.2
EEE60642.1
NP_001052344.1
Q7XSZ4 [T]
Q7XSZ4.2

cDNA clone:J023134L09, full insert sequence {ECO:0000313|EMBL:BAG93061.1} Oryza sativa subsp. japonica (Rice). BAD61107.1
BAF03949.1
BAG93061.1
NP_001042035.1
Q5ZEI3 [T]

Protein tyrosine phosphatase-like protein 4.2.1.134 {ECO:0000250|UniProtKB:Q8VZB2}
Oryza sativa subsp. japonica (Rice). BAD61100.1
BAF03946.1
BAG87629.1
EEE53880.1
NP_001042032.1
Q5ZEJ0 [T]
Q5ZEJ0.1

Protein-tyrosine phosphatase-like member A {ECO:0000305} 4.2.1.134 {ECO:0000250|UniProtKB:B0YJ81}
Ovis aries (Sheep). AAF29469.1
NP_001009443.1
Q9N1R5 [T]
Q9N1R5.1

Uncharacterized protein {ECO:0000313|Ensembl:ENSPTRP00000051117} Pan troglodytes (Chimpanzee).
XP_001168034.1
H2R830 [T]

Uncharacterized protein {ECO:0000313|Ensembl:ENSPTRP00000035596} Pan troglodytes (Chimpanzee).
XP_001148626.1
H2QX21 [T]

Ptpla domain protein {ECO:0000313|EMBL:BAM20400.1} Papilio polytes (Common mormon) (Swallowtail butterfly). BAM20400.1

I4DR60 [T]

Ptpla domain protein {ECO:0000313|EMBL:BAM19923.1} Papilio xuthus (Asian swallowtail butterfly). BAM19923.1

I4DPT3 [T]

Putative uncharacterized protein {ECO:0000313|EMBL:ABK26740.1} Picea sitchensis (Sitka spruce) (Pinus sitchensis). ABK26740.1

A9P1H9 [T]

Putative uncharacterized protein {ECO:0000313|EMBL:ABK21051.1} Picea sitchensis (Sitka spruce) (Pinus sitchensis). ABK21051.1

A9NK90 [T]

Protein-tyrosine phosphatase-like member B {ECO:0000305} 4.2.1.134 {ECO:0000250|UniProtKB:Q6Y1H2}
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii). CAH90857.1
NP_001125489.1
Q5RBK3 [T]
Q5RBK3.1

Putative uncharacterized protein DKFZp459B2333 {ECO:0000313|EMBL:CAH90274.1} Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii). CAH90274.1
NP_001128774.1
Q5RD83 [T]

Protein-tyrosine phosphatase-like A domain-containing protein 1 {ECO:0000305} 4.2.1.134 {ECO:0000250|UniProtKB:Q9P035}
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii). CAH92593.1
CAI29611.1
NP_001127566.1
Q5NVQ2 [T]
Q5NVQ2.1

Uncharacterized protein {ECO:0000313|EMBL:EEE91319.1} Populus trichocarpa (Western balsam poplar) (Populus balsamifera subsp. trichocarpa). ABK92807.1
EEE91319.1
XP_002310869.1
A9P8V4 [T]

Phs1p {ECO:0000313|EMBL:EWG85031.1} 4.2.1.134 {ECO:0000269|PubMed:17719544
ECO:0000269|PubMed:18272525}
Saccharomyces cerevisiae R008. AAS56181.1
AHY78908.1
AJP39609.1
AJR53878.1
AJR54205.1
AJR54869.1
AJR55193.1
AJR55503.1
AJR55831.1
AJR56160.1
AJR56485.1
AJR56812.1
AJR57140.1
AJR57469.1
AJR57797.1
AJR58125.1
AJR58452.1
AJR58777.1
AJR59104.1
AJR59430.1
AJR59760.1
AJR60085.1
AJR60417.1
AJR60745.1
AJR61070.1
AJR61397.1
AJR61720.1
AJR62381.1
AJR62708.1
AJR63032.1
AJR63357.1
AJR63688.1
AJR64019.1
AJR64337.1
AJR64903.1
AJR65231.1
AJR65562.1
AJR66216.1
AJR66538.1
AJR66864.1
AJR67192.1
AJR67523.1
AJR67816.1
AJR68144.1
AJR68461.1
AJR68786.1
AJR69095.1
AJR69426.1
AJR70089.1
AJR70417.1
AJR70753.1
AJR71403.1
AJR71717.1
AJR72046.1
AJR72375.1
AJR72701.1
AJR73030.1
AJR73362.1
AJR73693.1
AJR74006.1
AJR74323.1
AJR74654.1
AJR74989.1
AJR75318.1
AJR75649.1
AJV38667.1
AJV38995.1
AJV39314.1
AJV39969.1
AJV40286.1
AJV40611.1
AJV40940.1
AJV41268.1
AJV41589.1
AJV41917.1
AJV42243.1
AJV42569.1
AJV42900.1
AJV43229.1
AJV43562.1
AJV43881.1
AJV44208.1
AJV44538.1
AJV44864.1
AJV45191.1
AJV45525.1
AJV45808.1
CAA54893.1
CAA89391.1
CAY80683.2
DAA08703.1
EDN63480.1
EDV12669.1
EDZ71319.1
EEU06763.1
EGA82216.1
EHN06466.1
EIW09434.1
EWG85031.1
EWG90313.1
EWG95037.1
EWH17784.1
GAA24264.1
NP_012438.1
A0A023ZL43
A0A024XMM6
A0A024Y0G5
A6ZPM7
B3LQ16
B5VL76
C7GR17
C8ZBB7
E7KQA9
G2WGS1
H0GIA1
N1NZS6
P40857 [P]
P40857.1
W7PRH6
W7QX15

Clone ZZZ308 mRNA sequence {ECO:0000313|EMBL:AAP05971.1} Schistosoma japonicum (Blood fluke). AAP05971.1

Q86FA4 [T]

SJCHGC04764 protein {ECO:0000313|EMBL:AAX25715.2} Schistosoma japonicum (Blood fluke). AAX25715.2

Q5C3R0 [T]

Protein PHS1 {ECO:0000313|EMBL:CAX72739.1} Schistosoma japonicum (Blood fluke). CAX72739.1

C1LDG1 [T]

Protein tyrosine phosphatase-like protein {ECO:0000313|EMBL:ABG21826.1} Schistosoma mansoni (Blood fluke). ABG21826.1
CAZ29933.1

Q15ES5 [T]

Protein tyrosine phosphatase 1B {ECO:0000313|EMBL:ADK11696.1} Strongylocentrotus intermedius (Sea urchin). ADK11696.1

D9IVF2 [T]

Protein-tyrosine phosphatase-like A domain-containing protein 2 {ECO:0000305} 4.2.1.134 {ECO:0000250|UniProtKB:Q9P035}
Xenopus laevis (African clawed frog). AAH73600.1
NP_001085959.1
Q6GNB5 [T]
Q6GNB5.1

Uncharacterized protein {ECO:0000313|EMBL:ACF84320.1, ECO:0000313|EnsemblPlants:GRMZM2G151087_P02} Zea mays (Maize). ACF84320.1
ACF88349.1
ACG34736.1
ACR36120.1
NP_001142376.1
B4FQC7 [T]

PAS2 {ECO:0000313|EMBL:ACG31453.1} Zea mays (Maize). ACG31453.1

B6T2X0 [T]

Protein tyrosine phosphatase-like protein PTPLB {ECO:0000313|EMBL:ACG39999.1} Zea mays (Maize). ACG39999.1
NP_001150685.1
B6TSB6 [T]

Uncharacterized protein {ECO:0000313|EMBL:ACN32146.1, ECO:0000313|EnsemblPlants:GRMZM2G181266_P01} Zea mays (Maize). ACN32146.1
AFW80062.1
NP_001169265.1
XP_008655259.1
C0PDA1 [T]